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W. Schaafsma et al.
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Katie Maurer et al.
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Ischemic Preconditioning in White Matter: Magnitude and Mechanism
Margaret A. Hamner et al.
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Matthew C. Morris et al.
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Shih-Chin Cheng et al.
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Microglial pathology
Wolfgang J. Streit et al.
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Microglial Phenotype and Adaptation
B. J. L. Eggen et al.
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C. Schmidt et al.
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Urmila Maitra et al.
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Michael C. Schmid et al.
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Carlotta Costa et al.
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Alessia Perino et al.
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Costantino Iadecola et al.
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Ulrich Dirnagl et al.
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Beom Seok Park et al.
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Hu-Nan Sun et al.
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Interleukin-10 endogenously expressed in microglia prevents lipopolysaccharide-induced neurodegeneration in the rat cerebral cortex in vivo
Keun Woo Park et al.
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Polonca Prohinar et al.
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CS Jack et al.
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PI3Kγ modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects
E Patrucco et al.
CELL (2004)
Inhibition of toll-like receptor and cytokine signaling -: A unifying theme in ischemic tolerance
K Karikó et al.
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Role of microglia in central nervous system infections
RB Rock et al.
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Bactericidal/permeability-increasing protein (BPI) and lipopolysaccharide-binding protein (LBP): structure, function and regulation in host defence against Gram-negative bacteria
J Weiss
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High-yield isolation of murine microglia by mild trypsinization
J Saura et al.
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Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
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E Hirsch et al.
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