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Noncytotoxic ribonuclease, RNase T1, induces tumor cell death via hemagglutinating virus of Japan envelope vector
S Yuki et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
Structure and stability of the non-covalent swapped dimer of bovine seminal ribonuclease - An enzyme tailored to evade ribonuclease protein inhibitor
F Sica et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Highly selective toxic and proapoptotic effects of two dimeric ribonucleases on thyroid cancer cells compared to the effects of doxorubicin
D Spalletti-Cernia et al.
BRITISH JOURNAL OF CANCER (2004)
The power of two: protein dimerization in biology
NJ Marianayagam et al.
TRENDS IN BIOCHEMICAL SCIENCES (2004)
Oligomerization of bovine ribonuclease A: structural and functional features of its multimers
M Libonati et al.
BIOCHEMICAL JOURNAL (2004)
Immunotoxins and other conjugates: Preparation and general characteristics
G Fracasso et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2004)
Role of the hinge peptide and the intersubunit interface in the swapping of N-termini in dimeric bovine seminal RNase
C Ercole et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
Glycosylation and specific deamidation of ribonuclease B affect the formation of three-dimensional domain-swapped oligomers
G Gotte et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease
R Berisio et al.
FEBS LETTERS (2003)
The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative
F Sica et al.
PROTEINS-STRUCTURE FUNCTION AND GENETICS (2003)
Compensating effects on the cytotoxicity of ribonuclease A variants
KA Dickson et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Antitumor activity and other biological actions of oligomers of ribonuclease A
J Matousek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis
D Spalletti-Cernia et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action
A Bracale et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
Thermal aggregation of ribonuclease A - A contribution to the understanding of the role of 3D domain swapping in protein aggregation
G Gotte et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Ribonuclease inhibitor as an intracellular sentry
MC Haigis et al.
NUCLEIC ACIDS RESEARCH (2003)
Secretory ribonucleases are internalized by a dynamin-independent endocytic pathway
MC Haigis et al.
JOURNAL OF CELL SCIENCE (2003)
Structures of the two 3D domain-swapped RNase A trimers
YS Liu et al.
PROTEIN SCIENCE (2002)
Engineering the refolding pathway and the quaternary structure of seminal ribonuclease by newly introduced disuffide bridges
A Russo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Domain swapping in ribonuclease T1 allows the acquisition of double-stranded activity
DT Chen et al.
PROTEIN ENGINEERING (2002)
RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin
J Harder et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Stabilization of human pancreatic ribonuclease through mutation at its N-terminal edge
A Benito et al.
PROTEIN ENGINEERING (2002)
Glycine 38 is crucial for the ribonucleolytic activity of human pancreatic ribonuclease on double-stranded RNA
D Gaur et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
3D domain swapping: As domains continue to swap
Y Liu et al.
PROTEIN SCIENCE (2002)
A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells
C De Lorenzo et al.
FEBS LETTERS (2002)
The ribonucleolytic activity of angiogenin
PA Leland et al.
BIOCHEMISTRY (2002)
RNase 8, a novel RNase A superfamily ribonuclease expressed uniquely in placenta
JZ Zhang et al.
NUCLEIC ACIDS RESEARCH (2002)
Quantitative evaluation of the lengths of homobifunctional protein cross-linking reagents used as molecular rulers
NS Green et al.
PROTEIN SCIENCE (2001)
Endowing human pancreatic ribonuclease with toxicity for cancer cells
PA Leland et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The structure of an engineered domain-swapped ribonuclease dimer and its implications for the evolution of proteins toward oligomerization
A Canals et al.
STRUCTURE (2001)
Structural properties of trimers and tetramers of ribonuclease A
A Nenci et al.
PROTEIN SCIENCE (2001)
Crystal structure of the human prion protein reveals a mechanism for oligomerization
KJ Knaus et al.
NATURE STRUCTURAL BIOLOGY (2001)
Contribution of chain termini to the conformational stability and biological activity of onconase
E Notomista et al.
BIOCHEMISTRY (2001)
Ribonucleases and their antitumor activity
J Matousek
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY (2001)
Preparation of potent cytotoxic ribonucleases by cationization: Enhanced cellular uptake and decreased interaction with ribonuclease inhibitor by chemical modification of carboxyl groups
J Futami et al.
BIOCHEMISTRY (2001)
Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping
R Janowski et al.
NATURE STRUCTURAL BIOLOGY (2001)
Antitumor action of seminal ribonuclease, its dimeric structure, and its resistance to the cytosolic ribonuclease inhibitor
A Antignani et al.
BIOCHEMISTRY (2001)
A domain-swapped RNase A dimer with implications for amyloid formation
YS Liu et al.
NATURE STRUCTURAL BIOLOGY (2001)
Potent and specific antitumor effects of an anti-CD22-targeted cytotoxic ribonuclease: potential for the treatment of non-Hodgkin lymphoma
DL Newton et al.
BLOOD (2001)
Barnase-barstar interaction
RW Hartley
RIBONUCLEASES, PT A (2001)
A synapomorphic disulfide bond is critical for the conformational stability and cytotoxicity of an amphibian ribonuclease
PA Leland et al.
FEBS LETTERS (2000)
Thermodynamic stability of the two isoforms of bovine seminal ribonuclease
C Giancola et al.
BIOCHEMISTRY (2000)
Targeting activated lymphocytes with an entirely human immunotoxin analogue: Human pancreatic RNase1-human IL-2 fusion
K Psarras et al.
CYTOKINE (2000)
In vitro evolution of a dimeric variant of human pancreatic ribonuclease
N Russo et al.
BIOCHEMISTRY (2000)