Microstructure and Antimicrobial Properties of Bioactive Cobalt Co-Doped Copper Aluminosilicate Nanocrystallines

Eco-friendly copper aluminosilicate nanoparticles doped with cobalt nanoparticles were prepared via the sol-gel route. The samples were calcined at 800 degrees C to induce high crystallization, which would potentially enhance their structural, spectroscopic and antimicrobial properties. Structural and spectroscopic characterization were measured using X-ray diffraction, Field emission-scanning electron microscopy, Fourier Transformed Infrared, UV-Vis-absorbance and UV/Vis diffuse reflectance spectra. The product revealed the formation of a crystalline cubic phase of (CAS) and orthorhombic (beta -Co2SiO4) phase. The antimicrobial susceptibility testing of nanocrystalline CAS, 5Co-CAS and 9Co-CAS as magnetic nanocomposites was evaluated using agar diffusion and broth dilution methods against Escherichia coli, Salmonella enterica, Pseudomonas aeruginosa, Listeria monocytogenes, Staphylococcus aureus, Enterococcus faecalis, Candida albicans, and Aspergillus niger. The toxicity assays for each antiseptic were also conducted. The incorporation of cobalt ions in the silicate base material was observed to be highly cross-linked during the formation process. UV-Vis-absorbance for the samples gave a red shift and noticeable increases in the band gap with the values 1.42, 1.43, 1.52 and 1.50 eV, respectively. The results showed that 9Co-CAS was the most potent antiseptic followed by 5Co-CAS and CAS.