4.7 Article

A QSP Model for Predicting Clinical Responses to Monotherapy, Combination and Sequential Therapy Following CTLA-4, PD-1, and PD-L1 Checkpoint Blockade

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

A Computational Model of Neoadjuvant PD-1 Inhibition in Non-Small Cell Lung Cancer

Mohammad Jafarnejad et al.

AAPS JOURNAL (2019)

Review Biochemistry & Molecular Biology

Improving the generation and selection of virtual populations in quantitative systems pharmacology models

Theodore R. Rieger et al.

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2018)

Review Immunology

Update on Tumor Neoantigens and Their Utility: Why It Is Good to Be Different

Chung-Han Lee et al.

TRENDS IN IMMUNOLOGY (2018)

Article Oncology

Advances in personalized cancer immunotherapy

Kazuhiro Kakimi et al.

BREAST CANCER (2017)

Article Multidisciplinary Sciences

A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition

Chang Gong et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2017)

Letter Medicine, General & Internal

Tumor Mutational Burden and Response Rate to PD-1 Inhibition

Mark Yarchoan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Cell Biology

Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma

Manuel Fankhauser et al.

SCIENCE TRANSLATIONAL MEDICINE (2017)

Review Immunology

Mechanisms and Dynamics of T Cell-Mediated Cytotoxicity In Vivo

Stephan Halle et al.

TRENDS IN IMMUNOLOGY (2017)

Review Oncology

Novel cancer antigens for personalized immunotherapies: latest evidence and clinical potential

Gregory T. Wurz et al.

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2016)

Editorial Material Oncology

Sequential immunotherapy regimens-expect the unexpected

Patricio Serra-Bellver et al.

LANCET ONCOLOGY (2016)

Article Oncology

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

Suzanne L. Topalian et al.

CANCER CELL (2015)

Article Biochemistry & Molecular Biology

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth

Sonja Kleffel et al.

Editorial Material Cell Biology

T-cell repertoire The human T-cell repertoire grows up

James J. Moon et al.

IMMUNOLOGY AND CELL BIOLOGY (2015)

Review Multidisciplinary Sciences

Somatic mutation in cancer and normal cells

Inigo Martincorena et al.

SCIENCE (2015)

Review Oncology

The Interplay of Immunotherapy and Chemotherapy: Harnessing Potential Synergies

Leisha A. Emens et al.

CANCER IMMUNOLOGY RESEARCH (2015)

Review Engineering, Chemical

A Quantitative Systems Pharmacology Perspective on Cancer Immunology

Christina Byrne-Hoffman et al.

PROCESSES (2015)

Review Pharmacology & Pharmacy

Modeling the T cell immune response: a fascinating challenge

Penelope A. Morel et al.

JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2014)

Article Pharmacology & Pharmacy

Survey of monoclonal antibody disposition in man utilizing a minimal physiologically-based pharmacokinetic model

Yanguang Cao et al.

JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2014)

Article Pharmacology & Pharmacy

Modeling cancer-immune responses to therapy

L. G. dePillis et al.

JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2014)

Article Multidisciplinary Sciences

PD-1 blockade induces responses by inhibiting adaptive immune resistance

Paul C. Tumeh et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

Structure and Interactions of the Human Programmed Cell Death 1 Receptor

Xiaoxiao Cheng et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Medicine, General & Internal

Nivolumab plus Ipilimumab in Advanced Melanoma

Jedd D. Wolchok et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Review Immunology

The integration of T cell migration, differentiation and function

David Masopust et al.

NATURE REVIEWS IMMUNOLOGY (2013)

Review Immunology

Programmed Death Ligand 2 in Cancer-Induced Immune Suppression

Esdy N. Rozali et al.

CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2012)

Editorial Material Medicine, General & Internal

The High Cost of Cancer Drugs and What We Can Do About It

Mustaqeem Siddiqui et al.

MAYO CLINIC PROCEEDINGS (2012)

Article Medicine, General & Internal

Safety and Activity of Anti-PD-L1 Antibody in Patients with Advanced Cancer

Julie R. Brahmer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Medicine, General & Internal

Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer

Suzanne L. Topalian et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Mathematical & Computational Biology

Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies

Stacey D. Finley et al.

BMC SYSTEMS BIOLOGY (2011)

Article Oncology

Cancer Immunotherapy Comes of Age

Suzanne L. Topalian et al.

JOURNAL OF CLINICAL ONCOLOGY (2011)

Review Immunology

Strength of TCR-Peptide/MHC Interactions and In Vivo T Cell Responses

Emily Corse et al.

JOURNAL OF IMMUNOLOGY (2011)

Review Multidisciplinary Sciences

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

Robert D. Schreiber et al.

SCIENCE (2011)

Review Oncology

Chemokines Can Effector Cells Be Redirected to the Site of the Tumor?

Steven M. Dubinett et al.

CANCER JOURNAL (2010)

Article Multidisciplinary Sciences

PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

Michael A. Curran et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Pharmacology & Pharmacy

Antibody tumor penetration: Transport opposed by systemic and antigen-mediated clearance

Greg M. Thurber et al.

ADVANCED DRUG DELIVERY REVIEWS (2008)

Review Immunology

Cancer immunoediting from immune surveillance to immune escape

Ryungsa Kim et al.

IMMUNOLOGY (2007)

Article Pathology

Normal structure, function, and histology of lymph nodes

Cynthia L. Willard-Mack

TOXICOLOGIC PATHOLOGY (2006)

Article Multidisciplinary Sciences

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

TR Mempel et al.

NATURE (2004)

Article Immunology

Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes

MJ Miller et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2004)

Article Multidisciplinary Sciences

Dynamic imaging of T cell-dendritic cell interactions in lymph nodes

S Stoll et al.

SCIENCE (2002)