期刊
MATERIALS
卷 12, 期 20, 页码 -出版社
MDPI
DOI: 10.3390/ma12203340
关键词
silk fibroin; curcumin; sustained-release; antibacterial activity; cytotoxicity
类别
资金
- Chongqing Municipal Commission of Commerce [CQ2019JSCC03]
- Fundamental Research Funds for the Central Universities [XDJK2018C067]
- Start-up Fund of Southwest University [SWU117036]
- Chongqing Graduate Student Research Innovation Project [CYS19121]
In the present work, a sustained-release film composed of silk fibroin (SF), curcumin (Cur), glutaraldehyde (GA), and glycerol (Gly) was prepared successfully for wound dressings. Features relevant to wound dressings of SF/Gly/GA/Cur film were assessed. Physical and chemical properties of the fabricated materials were also characterized. The results showed that the prepared SF/Gly/GA/Cur film demonstrated a good sustained-release performance, flexibility, and gas permeability. In addition, it was found that the prepared SF/Gly/GA/Cur film possessed the capability to effectively inhibit the growth of bacteria and prevent bacterial penetration with a suitable water vapor transmission rate. Furthermore, the prepared composite film was non-cytotoxic, which makes it an ideal material for wound dressings.
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