相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling
Hsin-Yung Yen et al.
NATURE (2018)
Priming GPCR signaling through the synergistic effect of two G proteins
Tejas M. Gupte et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Conformational equilibria of light-activated rhodopsin in nanodiscs
Ned Van Eps et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
ER/K linked GPCR-G protein fusions systematically modulate second messenger response in cells
Rabia U. Malik et al.
SCIENTIFIC REPORTS (2017)
G protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning
Lauriane Onfroy et al.
SCIENTIFIC REPORTS (2017)
GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling
Alex R. B. Thomsen et al.
CELL (2016)
Structural Elements in the Gs and Gq C Termini That Mediate Selective G Protein-coupled Receptor (GPCR) Signaling
Ansley Semack et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists
Yi Zheng et al.
NATURE (2016)
Crystal structures of the M1 and M4 muscarinic acetylcholine receptors
David M. Thal et al.
NATURE (2016)
β-Arrestin drives MAP kinase signalling from clathrin-coated structures after GPCR dissociation
K. Eichel et al.
NATURE CELL BIOLOGY (2016)
Decay of an active GPCR: Conformational dynamics govern agonist rebinding and persistence of an active, yet empty, receptor state
Christopher T. Schafer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling
Aashish Manglik et al.
CELL (2015)
Conformational Memory of a Protein Revealed by Single-Molecule Spectroscopy
Mario Schoerner et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2015)
Propagation of conformational changes during μ-opioid receptor activation
Remy Sounier et al.
NATURE (2015)
Allostery vs. allokairy
Vincent J. Hilser et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Dual allosteric activation mechanisms in monomeric human glucokinase
A. Carl Whittington et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Comprehensive analysis of heterotrimeric G-protein complex diversity and their interactions with GPCRs in solution
Matthias Hillenbrand et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Harnessing the Unique Structural Properties of Isolated α-Helices
Carter J. Swanson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Development and Characterization of Pepducins as Gs-biased Allosteric Agonists
Richard Carr et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis
Nikoleta G. Tsvetanova et al.
NATURE CHEMICAL BIOLOGY (2014)
Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics
Lars Iversen et al.
SCIENCE (2014)
The Dynamic Process of β2-Adrenergic Receptor Activation
Rie Nygaard et al.
CELL (2013)
Detection of G Protein-selective G Protein-coupled Receptor (GPCR) Conformations in Live Cells
Rabia U. Malik et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Fiji: an open-source platform for biological-image analysis
Johannes Schindelin et al.
NATURE METHODS (2012)
NIH Image to ImageJ: 25 years of image analysis
Caroline A. Schneider et al.
NATURE METHODS (2012)
Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region
Yutaka Kofuku et al.
NATURE COMMUNICATIONS (2012)
Purification of Heterotrimeric G Protein α Subunits by GST-Ric-8 Association PRIMARY CHARACTERIZATION OF PURIFIED Gαolf
PuiYee Chan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Crystal structure of the β2 adrenergic receptor-Gs protein complex
Soren G. F. Rasmussen et al.
NATURE (2011)
Multiple ligand-specific conformations of the β2-adrenergic receptor
Alem W. Kahsai et al.
NATURE CHEMICAL BIOLOGY (2011)
Systematic control of protein interaction using a modular ER/K α-helix linker
Sivaraj Sivaramakrishnan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
mMass 3: A Cross-Platform Software Environment for Precise Analysis of Mass Spectrometric Data
Martin Strohalm et al.
ANALYTICAL CHEMISTRY (2010)
Differential Signaling of the Endogenous Agonists at the β2-Adrenergic Receptor
Susanne Reiner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
Michael P. Bokoch et al.
NATURE (2010)
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation
Yang Han et al.
NATURE CHEMICAL BIOLOGY (2009)
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
Xiao Jie Yao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
ProteoWizard: open source software for rapid proteomics tools development
Darren Kessner et al.
BIOINFORMATICS (2008)
Multiple-state reactions between the epidermal growth factor receotor and Grb2 as observed by using single-molecule analysis
Miki Morimatsu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
FRET-based monitoring of conformational change of the β2 adrenergic receptor in living cells
J Nakanishi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Targeted knockdown of G protein subunits selectively prevents receptor-mediated modulation of effectors and reveals complex changes in non-targeted signaling proteins
AM Krumins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited
BP English et al.
NATURE CHEMICAL BIOLOGY (2006)
Do enzymes sleep and work?
H Engelkamp et al.
CHEMICAL COMMUNICATIONS (2006)
Effects of urea pretreatment on the binding properties of adenosine A1 receptors
LT May et al.
BRITISH JOURNAL OF PHARMACOLOGY (2005)
Allosteric modulators of G-protein-coupled receptors
LT May et al.
CURRENT OPINION IN PHARMACOLOGY (2003)
Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors
E Hermans
PHARMACOLOGY & THERAPEUTICS (2003)
Conformational-relaxation models of single-enzyme kinetics
HP Lerch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Functionally different agonists induce distinct conformations in the G protein coupling domain of the β2 adrenergic receptor
P Ghanouni et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Memory landscapes of single-enzyme molecules
L Edman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
分享论文
