期刊
JOURNAL OF FUNCTIONAL FOODS
卷 64, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.jff.2019.103596
关键词
Anthocyanins; TNF-alpha; IL-6; CCL2; Chronic inflammation; Obesity
资金
- Griffith Health Institute and Gold Coast University Hospital Collaborative (GHIGCUH) Grant
Chronic low-grade inflammation in obese and overweight individuals is associated with an increased risk of type II diabetes and cardiovascular disease. The current trial investigated the anti-inflammatory properties of anthocyanin (ACN) supplementation in lean, overweight and obese individuals. Fifteen lean, ten overweight and ten obese participants consumed ACN (320 mg/day) for 28 days along with their usual diet. ACN supplementation significantly decreased blood plasma levels of CCL2 in the lean, overweight and obese groups (p < 0.0001, p < 0.0001 and p < 0.01 respectively). Additionally, significantly decreased levels of IL-6 in the obese group (p < 0.05) were also observed post-ACN supplementation. In conclusion, these results demonstrate the anti-inflammatory potential of ACN and suggest the supplementation of ACN as a complementary therapeutic agent for reducing chronic inflammation in obese and overweight individuals.
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