期刊
VIRUSES-BASEL
卷 11, 期 11, 页码 -出版社
MDPI
DOI: 10.3390/v11110979
关键词
virome; Manis javanica; Sendai virus; Coronavirus; molecular epidemiology
类别
资金
- GDAS' Project of Science and Technology Development [2019GDASYL-0302007, 2018GDASCX-0107]
- Guangzhou Science Technology and Innovation Commission [201804020080]
- Special Funds for Forestry Development and Protection of Guangdong Province (2019)
Pangolins are endangered animals in urgent need of protection. Identifying and cataloguing the viruses carried by pangolins is a logical approach to evaluate the range of potential pathogens and help with conservation. This study provides insight into viral communities of Malayan Pangolins (Manis javanica) as well as the molecular epidemiology of dominant pathogenic viruses between Malayan Pangolin and other hosts. A total of 62,508 de novo assembled contigs were constructed, and a BLAST search revealed 3600 ones (>= 300 nt) were related to viral sequences, of which 68 contigs had a high level of sequence similarity to known viruses, while dominant viruses were the Sendai virus and Coronavirus. This is the first report on the viral diversity of pangolins, expanding our understanding of the virome in endangered species, and providing insight into the overall diversity of viruses that may be capable of directly or indirectly crossing over into other mammals.
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