期刊
TRENDS IN IMMUNOLOGY
卷 40, 期 11, 页码 1022-1034出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.it.2019.09.002
关键词
-
类别
资金
- Institut Pasteur, Inserm
- Advanced grant (ENLIGHTEN) from the European Research Council
Understanding complex interactions between the immune system and the tumor microenvironment is an essential step towards the rational development and optimization of immunotherapies. Several experimental approaches are available to tackle this complexity but most are not designed to address the dynamic features of immune reactions, including cell migration, cellular interactions, and transient signaling events. By providing a unique means to access these precious parameters, intravital imaging offers a fresh look at intratumoral immune responses at the single-cell level. Here, we discuss how in vivo imaging sheds light on fundamental aspects of tumor immunity and helps elucidate modes of action of immunotherapies. We conclude by discussing future developments that may consolidate the unique contribution of intravital imagine for our understanding of tumor immunity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据