期刊
BIOTECHNOLOGY ADVANCES
卷 34, 期 3, 页码 177-197出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biotechadv.2015.12.005
关键词
Direct electron transfer; Mediated electron transfer; Immobilisation; Microbiosensor; Nanobiosensor; Paper-based biosensor; Wearable biosensor; Self-powered biosensor
We present a brief overview of bioelectrocatalytic devices for in vitro health applications, including food safety and environmental analysis, focusing on microelectrode- and microfluidic-based biosensors, paper-based point-of-care devices and wearable biosensors. The main hurdles and future perspectives are discussed. We then consider the role of electron transfer between a biocatalyst and an electrode in biosensor design. Brief descriptions of indirect, direct and mediated mechanisms are given. The principal strategies, as well as recent developments for modulation of electron transfer in biocatalytic systems are summarised. In conclusion, we highlight some of the challenges associated with improving these redox systems. (C) 2015 Elsevier Inc. All rights reserved.
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