Advances in chiral multidimensional liquid chromatography

It is well known that the chiral separation is different but very important in separation science. Increase in number of chiral centers makes the chiral separations more difficult. In this respect multidimensional chromatography is gaining importance in chiral separations. There is a great demand of multidimensional chromatography in the chiral separations. The present article describes the separation and identification various racemates using multidimensional chromatography i.e. high performance liquid chromatography, gas chromatography, super critical fluid chromatography, thin layer chromatography. Besides, the efforts were made to discuss the importance of chiral separations, multidimensional chromatography, future perspectives and challenges. Certainly, this article will be useful for the researchers, academicians, government authorities and industrial persons. (c) 2019 Elsevier B.V. All rights reserved.