期刊
SENSORS
卷 19, 期 21, 页码 -出版社
MDPI
DOI: 10.3390/s19214614
关键词
bio-impedance; intra-articular injection therapy; lock-in amplifier; monopolar injection needle; porcine tissue
资金
- Gachon University Gil Medical Center [2017-08]
- National Research Foundation of Korea [NRF-2017R1D1A1A09000712, 2018M3A9F1023690, 2019R1A2C1088680]
- National Research Foundation of Korea [2019R1A2C1088680] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
For successful intra-articular injection therapy, it is essential to accurately position the tip of the injection needle into the target joint area while administering the drug into the affected tissue. In this study, we investigated the feasibility of a monopolar injection needle and lock-in amplifier (LIA)-based impedance measurement system for detecting the tissue type where the needle tip is located. After positioning the monopolar injection needle tip into the dermis, hypodermis, or muscle layer of pork tissue, the electrical impedance was measured in the frequency range of 10 Hz to 10 kHz. We observed a difference in the results based on the tissue type where the needle was positioned (p-value < 0.01). Therefore, the monopolar injection needle with electrical impedance measurement can be used to improve intra-articular injection therapy through non-destructive and real-time monitoring of the needle position in the tissues.
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