期刊
SEMINARS IN NEUROLOGY
卷 39, 期 5, 页码 589-595出版社
THIEME MEDICAL PUBL INC
DOI: 10.1055/s-0039-1693005
关键词
Guillain-Barre syndrome; acute inflammatory demyelinating polyneuropathy; acute motor axonal polyneuropathy; Miller-Fisher syndrome
Guillain-Barre syndrome (GBS) is the leading cause of acute paralysis that can potentially affect all of the human population. GBS is believed to be an immune-mediated disease, possibly triggered by a recent infection, and driven by an immune attack targeting the peripheral nervous system. GBS can be divided into several subtypes depending on the phenotype, pathophysiology, and neurophysiological features. Unfortunately, morbidity and mortality rates are still high despite the current understanding of the pathophysiology and available treatment options. Additional research is still needed to shed more light into the pathogenesis for a better understanding and treatment of this condition.
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