期刊
SCRIPTA MATERIALIA
卷 172, 期 -, 页码 83-87出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.scriptamat.2019.07.011
关键词
High-entropy alloys; Biomaterials; Thermodynamic calculation; Solidification; Biocompatibility
类别
资金
- JSPS KAKENHI [18H05254, 18K04750, 19H05172]
- Council for Science, Technology and Innovation (CSTI)
- Cross-Ministerial Strategic Innovation Promotion Program (SIP)
- Innovative Design/Manufacturing Technologies program of the New Energy and Industrial Technology Development Organization (NEDO)
- Grants-in-Aid for Scientific Research [19H05172, 18K04750, 18H05254] Funding Source: KAKEN
Nobel non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys (HEM) for metallic biomaterials (bio-HEAs) were designed and developed. The pseudo-binary phase diagrams focusing on solidification were constructed by thermodynamic calculations. The shifting the alloy composition of the equiatomic TiNbTaZrMo bio-HEA can realize the drastic improvement of the deformability. Notably, the non-equiatomic Ti, Zr-rich composition stimulated the molecular interaction between biological cells and bio-HEA, indicating the possibility of the proposed non-equiatomic Ti-Nb-Ta-Zr-Mo HEM as an advanced biomaterial for bone tissue engineering applications. This is the first achievement for the alloy design including the control of alloy composition for the development of new bio-HEAs. (C) 2019 Acta Materialia Inc. Published by Elsevier Ltd.
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