期刊
SCIENCE OF THE TOTAL ENVIRONMENT
卷 705, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.scitotenv.2019.135810
关键词
Indoor air; Airborne endotoxin; Ozone; Particulate matter
资金
- Ministry of Science and Technology, Republic of China (Taiwan) [106-2314-B-037-067]
- Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan from The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project, Ministry of Education (MOE) in Taiwan [KMU-TC108A01-1]
- Wang Jhan-Yang public Trust Fund
Background: To date, the effect of household airborne pollutants on the association between airborne endotoxin and lung function of schoolchildren is unknown. Objectives: The objective of this study is to evaluate whether indoor air pollutants such as carbon monoxide (CO). carbon dioxide (CO2), nitrogen dioxide (NO2), sulfur dioxide (SO2), ozone (O-3), particulate matter with aerodynamic diameter <10 and 2.5 mu m (PM10, PM2.5) can modify the association between airborne endotoxin and school children's lung function in a heavy industrial city in Taiwan. Methods: We recruited 120 elementary school-age children in Kaohsiung City, Taiwan. Aerosol samples were collected on a filter membrane for 24 h period and then analyzed for endotoxin. Air pollutants were measured for 24 h in living rooms while school children's lung function was measured. The modification of air pollutants on the relationship between airborne endotoxin and children's lung function was estimated after adjusting the gender, age, height, weight, and case-control status. Results: We found that both O-3 and PM10 concentrations significantly modified the relationships between airborne endotoxin and school children's lung function. Among children living in homes with O-3 >= 0.01 ppm or PM10 >= 62 mu g/m(3), airborne endotoxin was negatively associated with lung functions, whereas among those living in homes with O-3 < 0.01 ppm or PM10 < 62 mu g/m(3), airborne endotoxin was positively associated with lung functions. Conclusions: The indoor air pollutant concentration of O-3 and PM10 modifies the association between airborne en- dotoxin and school children's lung function. (C) 2019 The Authors. Published by Elsevier B.
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