期刊
SCIENCE OF THE TOTAL ENVIRONMENT
卷 692, 期 -, 页码 233-239出版社
ELSEVIER
DOI: 10.1016/j.scitotenv.2019.07.237
关键词
Silver nanoparticles; Bioavailability; Protein shell; Algal photosynthesis; Casein; Ionic silver
资金
- Argenol Laboratories [28108]
- [GA-LC-02/2011]
Because of their biocide properties, silver nanoparticles (AgNPs) arc present in numerous consumer products. The biocidal properties of AgNPs are due to both the interactions between AgNP and cell membranes and the release of dissolved silver (Ag+). Recent studies emphasized the role of different nanopartide coatings in complex ing and storing Ag+. In this study, the availability of dissolved silver in the presence of algae was assessed for three AgNPs with different silver contents (59%, 34% and 7% of total Ag), silver core sizes and casein shell thicknesses. The impact of ionic silver on the photosynthetic yield of Chlamydomonas reinhardtii was used as a proxy to estimate the amount of ionic silver toxically active during in vivo assays. The results showed that cysteine, a strong silver ligand, mitigated the toxicity of AgNPs in all cases, demonstrating the key role of Ag+ in this toxicity. The results showed that the AgNPs presenting an intermediate level of silver (34%) were 10 times more effective in terms of total mass (EC50 ten times smaller) than those presenting more (59%) or less (7%) silver. The higher toxicity was due to the higher release of Ag+ under biotic conditions due to the high surfacejmass ratio of the nanopartide silver core. Protein shells played a minor role in altering the availability of Ag+, probably acting as intermediate reservoirs. This study highlighted the utility of a very sensitive biological endpoint (i.e., algal photosynthesis) for the optimization of ionic silver delivery by nanomaterials. (C) 2019 Elsevier B.V. All rights reserved.
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