期刊
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
卷 45, 期 4, 页码 487-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.rdc.2019.06.001
关键词
Rheumatoid arthritis; Treat to target; Disease activity; Remission; Ultrasound; DMARDs; Biologics
类别
Treatment of rheumatoid arthritis has evolved significantly over the past decades. Therapeutic advances have made clinical remission a feasible goal. Systematic treatment approaches taking into account objective measures of disease activity (treat to target/T2T) have been shown to result in better outcomes. This article reviews the latest information regarding T2T in rheumatoid arthritis, including a synopsis of the different disease activity scores available, new definitions of remission used in clinical trials and in routine clinical care, studies supporting a T2T approach, the role of imaging to guide treatment, and areas in which uncertainty remains.
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