MoS2/reduced graphene oxide as active hybrid material for the electrochemical detection of folic acid in human serum

In this study, a new matrix based on a molybdenum disulfide-reduced graphene oxide hybrid (MoS2-rGO) was prepared and characterized. Modification of a glassy carbon electrode (GCE) with MoS2-rGO (MG) using drop casting allowed for the selective analysis of folic acid in the presence of a variety of interference species with a limit of detection of 10 nM, a linear range between 0.01 mu M and 100 mu M with a sensitivity of 14 mu A mu M-1. In addition, the analytical performance of the proposed sensor was successfully conducted for the determination of folic acid in human serum samples, making MG-GC electrodes promising interfaces for bio-electrochemical applications. (C) 2016 Elsevier B.V. All rights reserved.