期刊
BIOSENSORS & BIOELECTRONICS
卷 79, 期 -, 页码 9-14出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2015.11.100
关键词
Lab-on-chip; Vaginosis; Immunochip; Immunoassay; Electrochemical Impedance Spectroscopy; Microfluidics; On-chip diagnosis; Candida albicans; Streptococcus agalactiae; Chlamydia trachomatis
Lower genital tract infections caused by both sexually and not-sexually transmitted pathogens in women are a key public health priority worldwide, especially in developing countries. Since standard analyses are time-consuming, appropriate therapeutic intervention is often neglected or delayed. Lab-on-chips and biosensors open new perspectives and offer innovative tools to simplify the diagnosis by medical staff, especially in countries with inadequate resources. Here we report a biosensing platform based on Electrochemical Impedance Spectroscopy (EIS) that allows multiplexed detection of Candida albicans, Streptococcus agalactiae and Chlamydia trachomatis with a single biochip, enabling a quick screening thanks to the presence of different immobilized antibodies, each specific for one of the different target pathogens. (C) 2015 Elsevier B.V. All rights reserved.
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