期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 80, 期 4, 页码 774-778出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09168451.2015.1127132
关键词
Apios americana Medik; isoflavone; estrogen agonistic activity; antioxidant activity; alpha-glucosidase inhibitory activity
类别
资金
- Japan Society for the Promotion of Science (JSPS) [25560064]
- Grants-in-Aid for Scientific Research [25560064, 15K10615] Funding Source: KAKEN
Four unique isoflavone aglycones (barpisoflavone A (1), 2-hydroxygenistein (2), 5-methylgenistein (3), and gerontoisoflavone A (4)) whose structures were related to genistein were prepared from the tuber of Apios americana Medik. We examined the estrogen receptor and androgen receptor binding activities, estrogen agonistic activities, antioxidant activities, and -glucosidase inhibitory activities of 1-4. The results obtained showed that 2 possessed potent and 1, 3, and 4 possessed moderate estrogen partial agonistic activities, 1 and 2 possessed moderate antioxidant activities, and 2 and 3 possessed moderate -glucosidase inhibitory activities.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据