期刊
PROGRESS IN POLYMER SCIENCE
卷 98, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.progpolymsci.2019.101161
关键词
Supercritical fluid; Lipase; Biodegradable polyester; Biomedical engineering; Microcapsule; Microcellular scaffold
资金
- Cornell Startup Fund by Cornell University
Supercritical fluid technology has emerged as a cost-effective and low-hazard alternative to solvent-based methodologies in polymer synthesis, pharmaceutical science, and related biomedical applications. In this review, we first briefly describe the distinctive features of a supercritical fluid, biodegradable polyesters, and lipases. We will then cover the latest progress of supercritical fluid technology in polymerization. Lipase-catalyzed polymerization in supercritical carbon dioxide (SC-CO2) will be the focus of the synthesis section. The last section presents the biomedical applications employing SC-CO2 polymerization, including microcapsule formation for drug delivery, microcellular scaffold fabrication, and SC-CO2 assisted processes for polymer-based treatments, such as surface functionalization, aerogel formation, and fine particle formation. Each topic is illustrated with the most successful examples. Understanding the current progress in SC-CO2 polymerization is an essential step to facilitate the exploration with this green technology in new research frontiers. (C) 2019 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据