期刊
PHYSIOLOGY
卷 34, 期 6, 页码 381-391出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00018.2019
关键词
Drosophila; epithelia; mechanobiology; morphogenesis; optogenetics
类别
资金
- National Science Foundation [CMMI 1751841]
- BWF Career Award at the Scientific Interface, Clare Boothe Luce Professorship
- Packard Fellowship
During embryonic development, spatial and temporal patterns of mechanical forces help to transform unstructured groups of cells into complex, functional tissue architectures. Here, we review emerging approaches to manipulate these patterns of forces to investigate the mechanical mechanisms that shape multicellular tissues, with a focus on recent experimental studies of epithelial tissue sheets in the embryo of the model organism Drosophila melanogaster.
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