期刊
NUCLEIC ACIDS RESEARCH
卷 48, 期 D1, 页码 D87-D92出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkz1001
关键词
-
资金
- Norwegian Research Council [288404, 187615]
- Helse Sor-Ost
- University of Oslo through the Centre for Molecular Medicine Norway (NCMM)
- Norwegian Cancer Society [197884]
- Canadian Institutes of Health Research [BOP-149430, PJT-162120]
- Genome Canada
- Genome British Columbia [SIP007, 255ONT, 275SIL]
- Michael Smith Foundation for Health Research [17746]
- Natural Sciences and Engineering Research Council of Canada [RGPIN-2017-06824]
- Weston Brain Institute [20R74681]
- CREATE programs
- Netherlands Organization for Scientific Research [452172015]
- Lundbeck Foundation
- Danish Cancer Foundation
- Danish Innovation Fund
- Danish Council for Independent Research
- French National Agency for Research [FloPiNet ANR-16-CE920023-01, ANR-10-LABX-49-01]
- Rutherford Fund Fellowship
- BC Children's Hospital Foundation andResearch Institute
- BBSRC [BB/N023358/1] Funding Source: UKRI
- MRC [MC_UP_1102/1, MC_EX_MR/S300007/1] Funding Source: UKRI
JASPAR (http://jaspar.genereg.net) is an open-access database of curated, non-redundant transcription factor (TF)-binding profiles stored as position frequency matrices (PFMs) for TFs across multiple species in six taxonomic groups. In this 8th release of JASPAR, the CORE collection has been expanded with 245 new PFMs (169 for vertebrates, 42 for plants, 17 for nematodes, 10 for insects, and 7 for fungi), and 156 PFMs were updated (125 for vertebrates, 28 for plants and 3 for insects). These new profiles represent an 18% expansion compared to the previous release. JASPAR 2020 comes with a novel collection of unvalidated TF-binding profiles for which our curators did not find orthogonal supporting evidence in the literature. This collection has a dedicated web form to engage the community in the curation of unvalidated TF-binding profiles. Moreover, we created a Q&A forum to ease the communication between the user community and JASPAR curators. Finally, we updated the genomic tracks, inference tool, and TF-binding profile similarity clusters. All the data is available through the JASPAR website, its associated RESTful API, and through the JASPAR2020 R/Bioconductor package.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据