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Ke Zhang et al.
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Corey T. McMillan et al.
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C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
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HUMAN MOLECULAR GENETICS (2015)
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C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration
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Johnathan Cooper-Knock et al.
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JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
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Annemarie Huebers et al.
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Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion
Adrian J. Waite et al.
NEUROBIOLOGY OF AGING (2014)
Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS
Zhaoming Su et al.
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Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
Xinmei Wen et al.
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C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins
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SCIENCE (2014)
Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells
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SCIENCE (2014)
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Yvonne S. Davidson et al.
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ACTA NEUROPATHOLOGICA (2013)
Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins
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Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS
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