期刊
NEUROCASE
卷 26, 期 1, 页码 36-41出版社
ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
DOI: 10.1080/13554794.2019.1696837
关键词
Huntington's disease; social cognition; theory of mind; behavioral symptoms; structural MRI
资金
- French Ministry of Health (PHRC) [ID-RCB: 2011-A00681-40]
- Hospital of Angers (France)
- French National Institute for Health and Medical Research (INSERM)
- France Huntington's Disease Association
Huntington's disease (HD) is a devastating illness, associated with progressive motor, behavioral and cognitive dysfunctions. However, some studies emphasized that social cognition impairment could occur prior to the onset of these other symptoms. Here, we report the case of a 47 years old patient with early manifest HD, whose complaint was mainly related to the behavioral sphere. He exhibited a significant impairment of Theory of Mind abilities as well as behavioral, and discrete motor symptoms without noticeable cognitive decline. This case study suggests that social cognition impairments and behavioral changes could be in some cases a feature of the disease and may represent a major disability, in early stages of manifest HD.
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