4.8 Article

Structure of an allosteric modulator bound to the CB1 cannabinoid receptor

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex

Kaavya Krishna Kumar et al.

Article Biochemistry & Molecular Biology

Orthosteric and allosteric action of the C5a receptor antagonists

Heng Liu et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Orthosteric and allosteric action of the C5a receptor antagonists

Heng Liu et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Review Multidisciplinary Sciences

Structural insights into G-protein-coupled receptor allostery

David M. Thal et al.

NATURE (2018)

Article Biotechnology & Applied Microbiology

New approaches and challenges to targeting the endocannabinoid system

Vincenzo Di Marzo

NATURE REVIEWS DRUG DISCOVERY (2018)

Article Biochemistry & Molecular Biology

Structural insights into the subtype-selective antagonist binding to the M2 muscarinic receptor

Ryoji Suno et al.

NATURE CHEMICAL BIOLOGY (2018)

Article Multidisciplinary Sciences

Crystal structures of agonist-bound human cannabinoid receptor CB1

Tian Hua et al.

NATURE (2017)

Article Biochemistry & Molecular Biology

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40

Jun Lu et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)

Article Medicine, General & Internal

Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome

Orrin Devinsky et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Biochemistry & Molecular Biology

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40

Jun Lu et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)

Article Chemistry, Medicinal

Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s)

Pushkar M. Kulkarni et al.

JOURNAL OF MEDICINAL CHEMISTRY (2016)

Article Biochemistry & Molecular Biology

Crystal Structure of the Human Cannabinoid Receptor CB1

Tian Hua et al.

Article Multidisciplinary Sciences

High-resolution crystal structure of the human CB1 cannabinoid receptor

Zhenhua Shao et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

Manipulation of Subunit Stoichiometry in Heteromeric Membrane Proteins

Claudio L. Morales-Perez et al.

STRUCTURE (2016)

Article Pharmacology & Pharmacy

CB1 Allosteric Modulator Org27569 Is an Antagonist/Inverse Agonist of ERK1/2 Signaling

Thomas F. Gamage et al.

CANNABIS AND CANNABINOID RESEARCH (2016)

Review Medicine, General & Internal

Cannabinoids for Medical Use A Systematic Review and Meta-analysis

Penny F. Whiting et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)

Article Multidisciplinary Sciences

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Yanyong Kang et al.

NATURE (2015)

Article Multidisciplinary Sciences

Structural dynamics and energetics underlying allosteric inactivation of the cannabinoid receptor CB1

Jonathan F. Fay et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemistry & Molecular Biology

Allosteric Modulation of a Cannabinoid G Protein-coupled Receptor BINDING SITE ELUCIDATION AND RELATIONSHIP TO G PROTEIN SIGNALING

Derek M. Shore et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

Pregnenolone Can Protect the Brain from Cannabis Intoxication

Monique Vallee et al.

SCIENCE (2014)

Review Psychology

The Endocannabinoid System and the Brain

Raphael Mechoulam et al.

ANNUAL REVIEW OF PSYCHOLOGY, VOL 64 (2013)

Article Pharmacology & Pharmacy

Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?

Javier Fernandez-Ruiz et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2013)

Article Multidisciplinary Sciences

Activation and allosteric modulation of a muscarinic acetylcholine receptor

Andrew C. Kruse et al.

NATURE (2013)

Article Pharmacology & Pharmacy

CB1 Receptor Allosteric Modulators Display Both Agonist and Signaling Pathway Specificity

Gemma L. Baillie et al.

MOLECULAR PHARMACOLOGY (2013)

Article Biochemistry & Molecular Biology

A Key Agonist-induced Conformational Change in the Cannabinoid Receptor CB1 Is Blocked by the Allosteric Ligand Org 27569

Jonathan F. Fay et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Multidisciplinary Sciences

Crystal Structure of a Lipid G Protein-Coupled Receptor

Michael A. Hanson et al.

SCIENCE (2012)

Article Biochemistry & Molecular Biology

Identification of Essential Cannabinoid-binding Domains STRUCTURAL INSIGHTS INTO EARLY DYNAMIC EVENTS IN RECEPTOR ACTIVATION

Joong-Youn Shim et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemical Research Methods

MolProbity: all-atom structure validation for macromolecular crystallography

Vincent B. Chen et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Article Biochemical Research Methods

Features and development of Coot

P. Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Biochemical Research Methods

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Review Pharmacology & Pharmacy

Should peripheral CB1 cannabinoid receptors be selectively targeted for therapeutic gain?

George Kunos et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2009)

Article Medicine, Research & Experimental

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice

Douglas Osei-Hyiaman et al.

JOURNAL OF CLINICAL INVESTIGATION (2008)

Article Pharmacology & Pharmacy

PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats

J. G. Horswill et al.

BRITISH JOURNAL OF PHARMACOLOGY (2007)

Article Pharmacology & Pharmacy

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro

A. Thomas et al.

BRITISH JOURNAL OF PHARMACOLOGY (2007)

Article Multidisciplinary Sciences

GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function

Daniel M. Rosenbaum et al.

SCIENCE (2007)

Article Chemistry, Multidisciplinary

Phaser crystallographic software

Airlie J. McCoy et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)

Article Pharmacology & Pharmacy

Allosteric modulation of the cannabinoid CB1 receptor

MR Price et al.

MOLECULAR PHARMACOLOGY (2005)

Article Biochemical Research Methods

PRODRG:: a tool for high-throughput crystallography of protein-ligand complexes

AW Schüttelkopf et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Article Biochemical Research Methods

Activation of the cannabinoid CB1 receptor may involve a W6.48/F3.36 rotamer toggle switch

R Singh et al.

JOURNAL OF PEPTIDE RESEARCH (2002)