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Valerie Petit et al.
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Akito Nakamura et al.
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Paola Falletta et al.
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Bo-Jhih Guan et al.
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Oliver D. K. Maddocks et al.
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RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma
Coralie Dorard et al.
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PD-L1 Expression and Immune Escape in Melanoma Resistance to MAPK Inhibitors
Hojabr Kakavand et al.
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Comprehensive translational control of tyrosine kinase expression by upstream open reading frames
K. Wethmar et al.
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Richard Marcotte et al.
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Francesco Iorio et al.
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Christopher J. Fiorese et al.
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Sara K. Young et al.
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Gao Zhang et al.
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Clive R. Bramham et al.
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Abigail S. Krall et al.
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Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling
Jianguo Wu et al.
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From Krebs to clinic: glutamine metabolism to cancer therapy (vol 16, pg 619, 2016)
Brian J. Altman et al.
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Scott A. Oakes et al.
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cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions
Linchong Sun et al.
CELL RESEARCH (2015)
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Lawrence N. Kwong et al.
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ERK2 Mediates Metabolic Stress Response to Regulate Cell Fate
Sejeong Shin et al.
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Asparagine Synthetase Expression and Phase I Study With L-Asparaginase Encapsulated in Red Blood Cells in Patients With Pancreatic Adenocarcinoma
Jean-Baptiste Bachet et al.
PANCREAS (2015)
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Boris Ratnikov et al.
ONCOTARGET (2015)
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Helen Rizos et al.
CLINICAL CANCER RESEARCH (2014)
Endoplasmic Reticulum (ER) Stress and Hypoxia Response Pathways Interact to Potentiate Hypoxia-inducible Factor 1 (HIF-1) Transcriptional Activity on Targets Like Vascular Endothelial Growth Factor (VEGF)
Ethel R. Pereira et al.
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Rui Chen et al.
JOURNAL OF CELL BIOLOGY (2014)
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Ji Zhang et al.
MOLECULAR CELL (2014)
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Valentina Gandin et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2014)
Improving Breast Cancer Survival Analysis through Competition-Based Multidimensional Modeling
Erhan Bilal et al.
PLOS COMPUTATIONAL BIOLOGY (2013)
Essential Gene Profiles in Breast, Pancreatic, and Ovarian Cancer Cells
Richard Marcotte et al.
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Rob Pieters et al.
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Nicholas T. Ingolia et al.
CELL (2011)
Regulation of mTORC1 Signaling by pH
Aruna D. Balgi et al.
PLOS ONE (2011)
eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression
Luc Furic et al.
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David R. Wise et al.
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Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans
Sarah E. Calvo et al.
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Michael S. Kilberg et al.
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MEK signaling is required for phosphorylation of eIF2α following amino acid limitation of HepG2 human hepatoma cells
Michelle M. Thiaville et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
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Hans-Guido Wendel et al.
GENES & DEVELOPMENT (2007)
Activating transcription factor 3, a stress-inducible gene, suppresses Ras-stimulated tumorigenesis
D Lu et al.
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Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia
WAG Stams et al.
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Metastasizing melanoma formation caused by expression of activated N-RasQ61K on an INK4a-deficient background
J Ackermann et al.
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Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
I Topisirovic et al.
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AP-1: A double-edged sword in tumorigenesis
R Eferl et al.
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MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
NL Sang et al.
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Role of MAP kinase in tumor progression and invasion
KB Reddy et al.
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A phase I and pharmacodynamic evaluation of polyethylene glycol-conjugated L-asparaginase in patients with advanced solid tumors
CW Taylor et al.
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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
R Sears et al.
GENES & DEVELOPMENT (2000)
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