相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。A microfluidic platform for physical entrapment of yeast cells with continuous production of invertase
Eduardo Js Bras et al.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY (2017)
Bottom-Up Protemics (2013-2015): Keeping up in the Era of Systems Biology
Janice Mayne et al.
ANALYTICAL CHEMISTRY (2016)
Continuous colorimetric screening assays for the detection of specific l- or d-α-amino acid transaminases in enzyme libraries
Egon Heuson et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2016)
Magic Ionization Mass Spectrometry
Sarah Trimpin
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2016)
Plasma-based ambient ionization mass spectrometry in bioanalytical sciences
Marek Smoluch et al.
MASS SPECTROMETRY REVIEWS (2016)
Norine, the knowledgebase dedicated to non-ribosomal peptides, is now open to crowdsourcing
Areski Flissi et al.
NUCLEIC ACIDS RESEARCH (2016)
High throughput strategies for the design, discovery, and analysis of biomaterials
Kristopher A. Kilian et al.
ACTA BIOMATERIALIA (2016)
Structural analysis of small to medium-sized molecules by mass spectrometry after electron-ion fragmentation (ExD) reactions
Yulin Qi et al.
ANALYST (2016)
Online Hydrophobic Interaction Chromatography-Mass Spectrometry for Top-Down Proteomics
Bifan Chen et al.
ANALYTICAL CHEMISTRY (2016)
Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues
Chad W. Chumbley et al.
ANALYTICAL CHEMISTRY (2016)
An improvement of surfactin production by B-subtilis BBG131 using design of experiments in microbioreactors and continuous process in bubbleless membrane bioreactor
Luiz Fernando Motta Dos Santos et al.
BIORESOURCE TECHNOLOGY (2016)
Microfluidic Tools Toward Industrial Biotechnology
Aline F. Oliveira et al.
BIOTECHNOLOGY PROGRESS (2016)
High-throughput platforms for metabolomics
Markus de Raad et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2016)
The microfluidic bioreactor for a new era of bioprocess development
Christian Blesken et al.
ENGINEERING IN LIFE SCIENCES (2016)
Rapid screening and identification of compounds with DNA-binding activity from Folium Citri Reticulatae using on-line HPLC-DAD-MSn coupled with a post column fluorescence detection system
Qingrong Fu et al.
FOOD CHEMISTRY (2016)
Recent Progress in CRISPR/Cas9 Technology
Yue Mei et al.
JOURNAL OF GENETICS AND GENOMICS (2016)
MALDI imaging mass spectrometry of Pacific White Shrimp L. vannamei and identification of abdominal muscle proteins
Kevin L. Schey et al.
PROTEOMICS (2016)
Revisiting cellulase production and redefining current strategies based on major challenges
Ramesh Chander Kuhad et al.
RENEWABLE & SUSTAINABLE ENERGY REVIEWS (2016)
Ambient ionization and miniature mass spectrometry system for chemical and biological analysis
Xiaoxiao Ma et al.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2016)
Crosslinking and Mass Spectrometry: An Integrated Technology to Understand the Structure and Function of Molecular Machines
Alexander Leitner et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
Characterizing Protein-Protein Interactions Using Mass Spectrometry: Challenges and Opportunities
Arne H. Smits et al.
TRENDS IN BIOTECHNOLOGY (2016)
Microbial metabolomics in open microscale platforms
Layla J. Barkal et al.
NATURE COMMUNICATIONS (2016)
Diastereomeric resolution directed towards chirality determination focussing on gas-phase energetics of coordinated sodium dissociation
Osamu Kanie et al.
SCIENTIFIC REPORTS (2016)
Burkholderia genome mining for nonribosomal peptidesynthetases reveals a great potential for novelsiderophores and lipopeptides synthesis
Qassim Esmaeel et al.
MICROBIOLOGYOPEN (2016)
The secondary metabolite bioinformatics portal: Computational tools to facilitate synthetic biology of secondary metabolite production
Tilmann Weber et al.
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY (2016)
Norine: A powerful resource for novel nonribosomal peptide discovery
M. Pupin et al.
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY (2016)
Applications of Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap Based High Resolution Mass Spectrometry in Metabolomics and Lipidomics
Manoj Ghaste et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Identification of DGAT2 Inhibitors Using Mass Spectrometry
Xuelei S. Song et al.
JOURNAL OF BIOMOLECULAR SCREENING (2016)
Direct Measurement of Intracellular Compound Concentration by RapidFire Mass Spectrometry Offers Insights into Cell Permeability
Laurie J. Gordon et al.
JOURNAL OF BIOMOLECULAR SCREENING (2016)
CRISPy-web: An online resource to design sgRNAs for CRISPR applications
Kai Blin et al.
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY (2016)
Optimization of Methanotrophic Growth and Production of Poly(3-Hydroxybutyrate) in a High-Throughput Microbioreactor System
Eric R. Sundstrom et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2015)
WGE: a CRISPR database for genome engineering
Alex Hodgkins et al.
BIOINFORMATICS (2015)
White biotechnology: State of the art strategies for the development of biocatalysts for biorefining
S. Heux et al.
BIOTECHNOLOGY ADVANCES (2015)
Microscale and miniscale fermentation and screening
Clemens Lattermann et al.
CURRENT OPINION IN BIOTECHNOLOGY (2015)
High-throughput screens in mammalian cells using the CRISPR-Cas9 system
Jingyu Peng et al.
FEBS JOURNAL (2015)
Sequence determinants of improved CRISPR sgRNA design
Han Xu et al.
GENOME RESEARCH (2015)
High-Throughput Screening in Protein Engineering: Recent Advances and Future Perspectives
Magdalena Wojcik et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
A Chromogenic Assay Suitable for High-Throughput Determination of Limit Dextrinase Activity in Barley Malt Extracts
Marie Bojstrup et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2015)
XL-MS: Protein cross-linking coupled with mass spectrometry
Andrew N. Holding
METHODS (2015)
A new antibiotic kills pathogens without detectable resistance
Losee L. Ling et al.
NATURE (2015)
Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains
Junwei Shi et al.
NATURE BIOTECHNOLOGY (2015)
Minimum Information about a Biosynthetic Gene cluster
Marnix H. Medema et al.
NATURE CHEMICAL BIOLOGY (2015)
antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters
Tilmann Weber et al.
NUCLEIC ACIDS RESEARCH (2015)
Microscale technology and biocatalytic processes: opportunities and challenges for synthesis
Roland Wohlgemuth et al.
TRENDS IN BIOTECHNOLOGY (2015)
CRISPR-Cas9 Based Engineering of Actinomycetal Genomes
Yaojun Tong et al.
ACS SYNTHETIC BIOLOGY (2015)
Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi
Ralph A. Cacho et al.
FRONTIERS IN MICROBIOLOGY (2015)
High-Efficiency Multiplex Genome Editing of Streptomyces Species Using an Engineered CRISPR/Cas System
Ryan E. Cobb et al.
ACS SYNTHETIC BIOLOGY (2015)
Top Down proteomics: Facts and perspectives
Adam D. Catherman et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Rapid assessment of oxygen transfer impact for Corynebacterium glutamicum
Friedrich Kaess et al.
BIOPROCESS AND BIOSYSTEMS ENGINEERING (2014)
A Fluorescent Hydrogel-Based Flow Cytometry High-Throughput Screening Platform for Hydrolytic Enzymes
Christian Pitzler et al.
CHEMISTRY & BIOLOGY (2014)
Computational tools for designing and engineering enzymes
Jiri Damborsky et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2014)
Characterization of a heat-active archaeal β-glucosidase from a hydrothermal spring metagenome
Carola Schroeder et al.
ENZYME AND MICROBIAL TECHNOLOGY (2014)
Automated high-throughput protein purification using an AKTApurifier and a CETAC autosampler
Daniel Yoo et al.
JOURNAL OF CHROMATOGRAPHY A (2014)
Facile immobilization of enzyme by entrapment using a plasma-deposited organosilicon thin film
Adil Elagli et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2014)
Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases
Robert J. Citorik et al.
NATURE BIOTECHNOLOGY (2014)
Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials
David Bikard et al.
NATURE BIOTECHNOLOGY (2014)
Prediction of Monomer Isomery in Florine: A Workflow Dedicated to Nonribosomal Peptide Discovery
Thibault Caradec et al.
PLOS ONE (2014)
Purifying biopharmaceuticals: knowledge-based chromatographic process development
Alexander T. Hanke et al.
TRENDS IN BIOTECHNOLOGY (2014)
Diffusion based kinetic selectivity modulation of enzymatic proteolysis in a microfluidic reactor: experimental analysis and stochastic modeling
Adil Elagli et al.
RSC ADVANCES (2014)
High throughput process development in biomanufacturing
Karol M. Lacki
CURRENT OPINION IN CHEMICAL ENGINEERING (2014)
Experimental design for in-house validation of a screening immunoassay kit. The case of a multiplex dipstick for Fusarium mycotoxins in cereals
Veronica M. T. Lattanzio et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2013)
Versatile synthesis of probes for high-throughput enzyme activity screening
Tristan de Rond et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2013)
Sensitive and Continuous Screening of Inhibitors of β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) at Single SPR Chips
Xinyao Yi et al.
ANALYTICAL CHEMISTRY (2013)
Non-linear kinetic modelling of reversible bioconversions: Application to the transaminase catalyzed synthesis of chiral amino-alcohols
L. Rios-Solis et al.
BIOCHEMICAL ENGINEERING JOURNAL (2013)
Review of microfluidic microbioreactor technology for high-throughput submerged microbiological cultivation
Hanaa M. Hegab et al.
BIOMICROFLUIDICS (2013)
Microtiter plates versus stirred mini-bioreactors in biocatalysis: A scalable approach
Mario A. P. Nunes et al.
BIORESOURCE TECHNOLOGY (2013)
Oxygen transfer characteristics of miniaturized bioreactor systems
Timothy V. Kirk et al.
BIOTECHNOLOGY AND BIOENGINEERING (2013)
Direct and indirect use of GFP whole cell biosensors for the assessment of bioprocess performances: Design of milliliter scale-down bioreactors
Alison Brognaux et al.
BIOTECHNOLOGY PROGRESS (2013)
Cloning and characterization of a novel cold-active glycoside hydrolase family 1 enzyme with β-glucosidase, β-fucosidase and β-galactosidase activities
Anna Wierzbicka-Wos et al.
BMC BIOTECHNOLOGY (2013)
Strategies for the discovery and engineering of enzymes for biocatalysis
Timo Davids et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2013)
Computer-aided solvent screening for biocatalysis
J. Abildskov et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2013)
The development of a capillary microreactor for transesterification reactions using lipase immobilized onto a silica monolith
Sabiqah Tuan Anuar et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2013)
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
Wenyan Jiang et al.
NATURE BIOTECHNOLOGY (2013)
Characterization of a new and thermostable esterase from a metagenomic library
Yanbing Zhu et al.
MICROBIOLOGICAL RESEARCH (2013)
ClusterMine360: a database of microbial PKS/NRPS biosynthesis
Kyle R. Conway et al.
NUCLEIC ACIDS RESEARCH (2013)
New integrated bioprocess for the continuous production, extraction and purification of lipopeptides produced by Bacillus subtilis in membrane bioreactor
Francois Coutte et al.
PROCESS BIOCHEMISTRY (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
Continuous downstream processing of biopharmaceuticals
Alois Jungbauer
TRENDS IN BIOTECHNOLOGY (2013)
Development and Validation of a High-Throughput Intrinsic ATPase Activity Assay for the Discovery of MEKK2 Inhibitors
Syed Ahmad et al.
JOURNAL OF BIOMOLECULAR SCREENING (2013)
Compartmentalization of Electrophoretically Separated Analytes in a Multiphase Microfluidic Platform
Mark C. Draper et al.
ANALYTICAL CHEMISTRY (2012)
Self-Regulated, Droplet-Based Sample Chopper for Microfluidic Absorbance Detection
Kennon S. Deal et al.
ANALYTICAL CHEMISTRY (2012)
Modeling of permeabilization process in Pseudomonas putida G7 for enhanced limonin bioconversion
Meenakshi Malik et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2012)
New miniature stirred-tank bioreactors for parallel study of enzymatic biomass hydrolysis
Peter Riedlberger et al.
BIORESOURCE TECHNOLOGY (2012)
Mini-scale bioprocessing systems for highly parallel animal cell cultures
Beum Jun Kim et al.
BIOTECHNOLOGY PROGRESS (2012)
Directed Evolution of Highly Selective Proteases by Using a Novel FACS-Based Screen that Capitalizes on the p53 Regulator MDM2
Tae Hyeon Yoo et al.
CHEMBIOCHEM (2012)
Picoliter Cell Lysate Assays in Microfluidic Droplet Compartments for Directed Enzyme Evolution
Balint Kintses et al.
CHEMISTRY & BIOLOGY (2012)
Modeling and kinetic parameter estimation of alcohol dehydrogenase-catalyzed hexanol oxidation in a microreactor
Ana Tusek et al.
ENGINEERING IN LIFE SCIENCES (2012)
Enzymatic Synthesis of Ascorbyl Palmitate in Organic Solvents: Process Optimization and Kinetic Evaluation
Lindomar A. Lerin et al.
FOOD AND BIOPROCESS TECHNOLOGY (2012)
β-Galactosidase-immobilised microreactor fabricated using a novel technique for enzyme immobilisation and its application for continuous synthesis of lactulose
Yoon Seok Song et al.
FOOD CHEMISTRY (2012)
Evidence for Irreversible Inhibition of Glycogen Synthase Kinase-3β by Tideglusib
Juan Manuel Dominguez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Genome shuffling of Bacillus amyloliquefaciens for improving antimicrobial lipopeptide production and an analysis of relative gene expression using FQ RT-PCR
Junfeng Zhao et al.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2012)
Epoxidation of oleic acid catalyzed by PSCI-Amano lipase optimized by experimental design
Flavia de Abreu Correa et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2012)
Functionalization of polycarbonate with proteins; open-tubular enzymatic microreactors
D. Ogonczyk et al.
LAB ON A CHIP (2012)
On-chip continuous monitoring of motile microorganisms on an ePetri platform
Seung Ah Lee et al.
LAB ON A CHIP (2012)
An automated workflow for enhancing microbial bioprocess optimization on a novel microbioreactor platform
Peter Rohe et al.
MICROBIAL CELL FACTORIES (2012)
Palm oil hydrolysis catalyzed by lipases under ultrasound irradiation - The use of experimental design as a tool for variables evaluation
Karen M. Goncalves et al.
ULTRASONICS SONOCHEMISTRY (2012)
Highly sensitive terahertz spectroscopy in microsystem
Simon Laurette et al.
RSC ADVANCES (2012)
Computational approaches for rational design of proteins with novel functionalities
Manish Kumar Tiwari et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2012)
THE FUNGI: 1, 2, 3 ... 5.1 MILLION SPECIES?
Meredith Blackwell
AMERICAN JOURNAL OF BOTANY (2011)
Ultrafast Surface Enhanced Resonance Raman Scattering Detection in Droplet-Based Microfluidic Systems
Michael P. Cecchini et al.
ANALYTICAL CHEMISTRY (2011)
A Combination of In Vivo Selection and Cell Sorting for the Identification of Enantioselective Biocatalysts
Elena Fernandez-Alvaro et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Regulatory and metabolic network of rhamnolipid biosynthesis: Traditional and advanced engineering towards biotechnological production
Markus Michael Mueller et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2011)
Rapid Steps in the glmS Ribozyme Catalytic Pathway: Cation and Ligand Requirements
Krista M. Brooks et al.
BIOCHEMISTRY (2011)
Screening of cellulases for biofuel production: Online monitoring of the enzymatic hydrolysis of insoluble cellulose using high-throughput scattered light detection
Gernot Jaeger et al.
BIOTECHNOLOGY JOURNAL (2011)
Green fluorescent protein (GFP) leakage from microbial biosensors provides useful information for the evaluation of the scale-down effect
Frank Delvigne et al.
BIOTECHNOLOGY JOURNAL (2011)
A New Microfluidic Concept for Parallel Operated Milliliter-Scale Stirred Tank Bioreactors
Gabi Gebhardt et al.
BIOTECHNOLOGY PROGRESS (2011)
Screening for Enzyme Activity In Turbid Suspensions with Scattered Light
Robert Huber et al.
BIOTECHNOLOGY PROGRESS (2011)
Utilizing high-throughput experimentation to enhance specific productivity of an E.coli T7 expression system by phosphate limitation
Robert Huber et al.
BMC BIOTECHNOLOGY (2011)
A continuous membrane microbioreactor system for development of integrated pectin modification and separation processes
Muhd Nazrul Hisham Zainal Alam et al.
CHEMICAL ENGINEERING JOURNAL (2011)
Metabolic diversity among main microorganisms inside an arsenic-rich ecosystem revealed by meta- and proteo-genomics
Philippe N. Bertin et al.
ISME JOURNAL (2011)
Separation science is the key to successful biopharmaceuticals
Georges Guiochon et al.
JOURNAL OF CHROMATOGRAPHY A (2011)
Adding value to a toxic residue from the biodiesel industry: production of two distinct pool of lipases from Penicillium simplicissimum in castor bean waste
Mateus G. Godoy et al.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2011)
Application of response surface design to solvent, temperature and lipase selection for optimal monoglyceride production
Diana Marcela Cetina et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2011)
Proteomics for routine identification of microorganisms
Martin Welker
PROTEOMICS (2011)
High-throughput process development for biopharmaceutical drug substances
Rahul Bhambure et al.
TRENDS IN BIOTECHNOLOGY (2011)
A Flow Cytometry-Based Screening System for Directed Evolution of Proteases
Ran Tu et al.
JOURNAL OF BIOMOLECULAR SCREENING (2011)
Improvement of a two-stage fermentation process for docosahexaenoic acid production by Aurantiochytrium limacinum SR21 applying statistical experimental designs and data analysis
Silvina Mariana Rosa et al.
BIORESOURCE TECHNOLOGY (2010)
Microfluidic BioLector-Microfluidic Bioprocess Control in Microtiter Plates
Matthias Funke et al.
BIOTECHNOLOGY AND BIOENGINEERING (2010)
SMURF: Genomic mapping of fungal secondary metabolite clusters
Nora Khaldi et al.
FUNGAL GENETICS AND BIOLOGY (2010)
Optimized enzymatic synthesis of levulinate ester in solvent-free system
Alice Lee et al.
INDUSTRIAL CROPS AND PRODUCTS (2010)
Uncultured microorganisms as a source of secondary metabolites
Kim Lewis et al.
JOURNAL OF ANTIBIOTICS (2010)
High-Throughput Identification of Bacteria and Yeast by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry in Conventional Medical Microbiology Laboratories
S. Q. van Veen et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2010)
Ultrahigh-throughput screening in drop-based microfluidics for directed evolution
Jeremy J. Agresti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Application of microbioreactors in fermentation process development: a review
Daniel Schapper et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2009)
High-throughput screening for ionic liquids dissolving (ligno-)cellulose
Michael Zavrel et al.
BIORESOURCE TECHNOLOGY (2009)
Cold plasma functionalized TeraHertz BioMEMS for enzyme reaction analysis
Abdennour Abbas et al.
BIOSENSORS & BIOELECTRONICS (2009)
Using Electrospray Ionisation Mass Spectrometry to Study Non-Covalent Interactions
Bryan J. McCullough et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2009)
The 'rare biosphere': a reality check
Jens Reeder et al.
NATURE METHODS (2009)
Robo-Lector - a novel platform for automated high-throughput cultivations in microtiter plates with high information content
Robert Huber et al.
MICROBIAL CELL FACTORIES (2009)
Fabrication of microfluidic devices incorporating bead-based reaction and microarray-based detection system for enzymatic assay
Dae Nyun Kim et al.
SENSORS AND ACTUATORS B-CHEMICAL (2009)
Rational and systematic protein purification process development: the next generation
Beckley K. Nfor et al.
TRENDS IN BIOTECHNOLOGY (2009)
Single-cell high-throughput screening to identify enantioselective hydrolytic enzymes
Stefan Becker et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Quality control of DNA break metabolism: in the 'end', it's a good thing
Roland Kanaar et al.
EMBO JOURNAL (2008)
ClustScan: an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures
Antonio Starcevic et al.
NUCLEIC ACIDS RESEARCH (2008)
Microtiter plates as mini-bioreactors: miniaturization of fermentation methods
Wouter A. Duetz
TRENDS IN MICROBIOLOGY (2007)
MALDI imaging mass spectrometry: molecular snapshots of biochemical systems
Dale S. Cornett et al.
NATURE METHODS (2007)
Analysis of protein complexes using mass spectrometry
Anne-Claude Gingras et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Solution phase enantioselective recognition and discrimination by electrospray ionization - Mass spectrometry: State-of-the-art, methods, and an eye towards increased throughput measurements
Kevin A. Schug
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2007)
Selection strategies for improved biocatalysts
Ykelien L. Boersma et al.
FEBS JOURNAL (2007)
Mass spectrometry for enzyme assays and inhibitor screening: An emerging application in pharmaceutical research
Kenneth D. Greis
MASS SPECTROMETRY REVIEWS (2007)
Methods for samples preparation in proteomic research
Anna Bodzon-Kulakowska et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2007)
Downstream processing of monoclonal antibodies - Application of platform approaches
Abhinav A. Shukla et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2007)
Facile preparation of an enzyme-immobilized microreactor using a cross-linking enzyme membrane on a microchannel surface
Takeshi Honda et al.
ADVANCED SYNTHESIS & CATALYSIS (2006)
Multiple microfermentor battery: a versatile tool for use with automated parallel cultures of microorganisms producing recombinant proteins and for optimization of cultivation protocols
Emmanuel Frachon et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2006)
Automated high-throughput process for site-directed mutagenesis, production, purification, and kinetic characterization of enzymes
Raphael Carapito et al.
ANALYTICAL BIOCHEMISTRY (2006)
Control and detection of chemical reactions in microfluidic systems
Andrew J. deMello
NATURE (2006)
Miniature bioreactors: current practices and future opportunities
Jonathan I. Betts et al.
MICROBIAL CELL FACTORIES (2006)
Membranes and microfluidics: a review
J. de Jong et al.
LAB ON A CHIP (2006)
Miniature bioreactors for automated high-throughput bioprocess design (HTBD):: reproducibility of parallel fed-batch cultivations with Escherichia coli
R Puskeiler et al.
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY (2005)
High-throughput screening for enzyme inhibitors using frontal affinity chromatography with liquid chromatography and mass spectrometry
ESM Ng et al.
ANALYTICAL CHEMISTRY (2005)
Sphingolipidomics: High-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry
AH Merrill et al.
METHODS (2005)
Membrane-aerated microbioreactor for high-throughput bioprocessing
A Zanzotto et al.
BIOTECHNOLOGY AND BIOENGINEERING (2004)
On-line coupling of high-performance liquid chromatography to a continuous-flow enzyme assay based on electrospray ionization mass spectrometry
AR de Boer et al.
ANALYTICAL CHEMISTRY (2004)
Printing chemical libraries on microarrays for fluid phase nanoliter reactions
DN Gosalia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Enzymatic profiling system in a small-molecule microarray
Q Zhu et al.
ORGANIC LETTERS (2003)
Self-assembled monolayers that transduce enzymatic activities to electrical signals
WS Yeo et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Electrospray ionization tandem mass spectrometry in high-throughput screening of homogeneous catalysts
P Chen
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Peptide microarrays for the determination of protease substrate specificity
CM Salisbury et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles
J Piel
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Second-generation MS-based high-throughput screening system for enantioselective catalysts and biocatalysts
W Schrader et al.
CANADIAN JOURNAL OF CHEMISTRY (2002)
Sol-gel encapsulated enzyme arrays for high-throughput screening of biocatalytic activity
CB Park et al.
BIOTECHNOLOGY AND BIOENGINEERING (2002)
Carbohydrate arrays for the evaluation of protein binding and enzymatic modification
BT Houseman et al.
CHEMISTRY & BIOLOGY (2002)
Miniaturized HTS technologies -: uHTS
J Wölcke et al.
DRUG DISCOVERY TODAY (2001)
Introduction to advantages and problems of shaken cultures
J Büchs
BIOCHEMICAL ENGINEERING JOURNAL (2001)
The application of micro reactors to synthetic chemistry
SJ Haswell et al.
CHEMICAL COMMUNICATIONS (2001)
分享论文
