期刊
BIOPROCESS AND BIOSYSTEMS ENGINEERING
卷 40, 期 2, 页码 161-180出版社
SPRINGER
DOI: 10.1007/s00449-016-1690-x
关键词
Biotechnologies; Characterization; Enzyme catalysis; High-throughput screening
资金
- French National Research Agency (ANR) ['ANR-11-EQPX0037']
- Nord-Pas-de-Calais Region
- FEDER
- Universite Lille 1 Sciences AMP
- Technologies (USTL)
- Ecole Centrale de Lille (ECLille)
- Universite Lille 1, Sciences et Technologies
- ARCIR funds from Nord-Pas-de-Calais
- ANR (BtSurf)
- European Funds of INTERREG IV PhytoBio Project
- ERA-IB MESIAB
- ITN Marie Curie AMBER [317338]
Innovations in novel enzyme discoveries impact upon a wide range of industries for which biocatalysis and biotransformations represent a great challenge, i. e., food industry, polymers and chemical industry. Key tools and technologies, such as bioinformatics tools to guide mutant library design, molecular biology tools to create mutants library, microfluidics/microplates, parallel miniscale bioreactors and mass spectrometry technologies to create high-throughput screening methods and experimental design tools for screening and optimization, allow to evolve the discovery, development and implementation of enzymes and whole cells in (bio) processes. These technological innovations are also accompanied by the development and implementation of clean and sustainable integrated processes to meet the growing needs of chemical, pharmaceutical, environmental and biorefinery industries. This review gives an overview of the benefits of highthroughput screening approach from the discovery and engineering of biocatalysts to cell culture for optimizing their production in integrated processes and their extraction/ purification.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据