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Kendell Clement et al.
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Holly A. Rees et al.
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Luke W. Koblan et al.
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CRISPR-Cas9 genome editing induces a p53-mediated DNA damage response
Emma Haapaniemi et al.
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Max W. Shen et al.
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Membrane-associated guanylate kinase dynamics reveal regional and developmental specificity of synapse stability
Jonathan M. Levy et al.
JOURNAL OF PHYSIOLOGY-LONDON (2017)
Programmable base editing of A.T to G.C in genomic DNA without DNA cleavage
Nicole M. Gaudelli et al.
NATURE (2017)
Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions
Y. Bill Kim et al.
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ClinVar: public archive of interpretations of clinically relevant variants
Melissa J. Landrum et al.
NUCLEIC ACIDS RESEARCH (2016)
Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance
Ahmed H. Badran et al.
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Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9
Dominik Paquet et al.
NATURE (2016)
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Alexis C. Komor et al.
NATURE (2016)
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects
Benjamin P. Kleinstiver et al.
NATURE (2016)
Reprogramming eukaryotic translation with ligand-responsive synthetic RNA switches
Andrew V. Anzalone et al.
NATURE METHODS (2016)
Human exonuclease 1 (EXO1) activity characterization and its function on flap structures
Guido Keijzers et al.
BIOSCIENCE REPORTS (2015)
A naturally occurring variant of the human prion protein completely prevents prion disease
Emmanuel A. Asante et al.
NATURE (2015)
Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
Takeshi Maruyama et al.
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Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
Van Trung Chu et al.
NATURE BIOTECHNOLOGY (2015)
Therapeutic genome editing: prospects and challenges
David Benjamin Turitz Cox et al.
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limma powers differential expression analyses for RNA-sequencing and microarray studies
Matthew E. Ritchie et al.
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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Shengdar Q. Tsai et al.
NATURE BIOTECHNOLOGY (2015)
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
Hiroshi Nishimasu et al.
CELL (2014)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
J. Ross Chapman et al.
MOLECULAR CELL (2012)
Generation and characterization of new highly thermostable and processive M-MuLV reverse transcriptase variants
Aurimas Baranauskas et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Bo Li et al.
BMC BIOINFORMATICS (2011)
PCRless library mutagenesis via oligonucleotide recombination in yeast
Nathan Pirakitikulr et al.
PROTEIN SCIENCE (2010)
The naturally split Npu DnaE intein exhibits an extraordinarily high rate in the protein trans-splicing reaction
Joachim Zettler et al.
FEBS LETTERS (2009)
A Novel Protective Prion Protein Variant that Colocalizes with Kuru Exposure
Simon Mead et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Novel mutations in Moloney Murine Leukemia Virus reverse transcriptase increase thermostability through tighter binding to template-primer
Bahram Arezi et al.
NUCLEIC ACIDS RESEARCH (2009)
CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA
Luciano A. Marraffini et al.
SCIENCE (2008)
CRISPR provides acquired resistance against viruses in prokaryotes
Rodolphe Barrangou et al.
SCIENCE (2007)
Flap endonuclease 1: A central component of DNA metabolism
Y Liu et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2004)
Retroelements and the human genome: New perspectives on an old relation
N Bannert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Human synapsin 1 gene promoter confers highly neuron-specific long-term transgene expression from an adenoviral vector in the adult rat brain depending on the transduced area
S Kügler et al.
GENE THERAPY (2003)
The role of template-primer in protection of reverse transcriptase from thermal inactivation
GF Gerard et al.
NUCLEIC ACIDS RESEARCH (2002)
Role of murine leukemia virus reverse transcriptase deoxyribonucleoside triphosphate-binding site in retroviral replication and in vivo fidelity
EK Halvas et al.
JOURNAL OF VIROLOGY (2000)