期刊
MITOCHONDRION
卷 49, 期 -, 页码 83-88出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.mito.2019.07.007
关键词
ADHD; Biomarkers; Mitochondrion; Protein; Dopamine
资金
- Chang Gung Memorial Hospital Research Projects [CMRPG8F1291]
This study aimed to determine the role of mitochondria-associated proteins (HtrA2, alpha-synuclein, and Park7) in attention deficit/hyperactivity disorder (ADHD). A total of 125 patients with ADHD (77.6% were males) and 66 healthy controls (66.7% were males) were recruited. We found that girls with ADHD demonstrated higher plasma HtrA2 level than control girls, and their HtrA2 levels were positively correlated with verbal comprehensive ability, and negatively correlated to behavior symptoms. Among boys, we observed no correlations between these mitochondrial proteins, neuropsychological findings, and clinical symptoms. Our findings suggest that an underlying gender-specific mitochondria pathway may influence with the pathophysiology of ADHD.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据