期刊
MICROBIOLOGICAL RESEARCH
卷 227, 期 -, 页码 -出版社
ELSEVIER GMBH
DOI: 10.1016/j.micres.2019.06.003
关键词
Toxoplasma gondii; Life cycle; Secretory proteins; Parasite invasion
类别
资金
- Natural Science Foundation of Shenzhen City [JCYJ20170307150444573, JCYJ20180306172131515]
T. gondii is a major opportunistic pathogen chronically infecting nearly one third of the world's population. Due to the high infection and mortality rates in immunocompromised patients and newborns, the extent or magnitude of T. gondii pathogenesis is determined mainly by host-pathogen interactions. T. gondii utilizes specialized secretory proteins to modify host cellular factors and facilitate invasion and replication. This review provides update on the recent progress in this field of research with particular emphasis on the T. gondii secretory proteins and their role in invasion and pathogenesis.
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