4.2 Article

'Click' synthesis of cobalt bis(dicarbollide)-cholesterol conjugates

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MENDELEEV COMMUNICATIONS
卷 29, 期 6, 页码 628-630

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ELSEVIER
DOI: 10.1016/j.mencom.2019.11.007

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资金

  1. Russian Foundation for Basic Research [17-53-80099_ BRICS, 17-03-00476_a]
  2. Department of Science and Technology, Government of India [DST/IMRCD/BRICS/PilotCall1/BGNCDT/2017(G)]
  3. National Natural Science Foundation of China [51761145021]
  4. Ministry of Science and Higher Education of the Russian Federation

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New conjugates of cholesterol and cobalt bis(dicarbollide) were synthesized using 'click' cycloaddition of 3 beta-(2-azidoethyl)cholest-5-ene and acetylene-equipped cobalt bis(dicarbollides). The synthesized boronated cholesterols can be of interest for liposomal drug delivery for boron neutron capture therapy of cancer.

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