期刊
MARINE DRUGS
卷 17, 期 12, 页码 -出版社
MDPI
DOI: 10.3390/md17120653
关键词
scallop; paralytic shellfish toxins; tetrodotoxin; HILIC-MS; MS; Alexandrium tamarense
资金
- Japan Society for the Promotion of Science (JSPS) through its KAKENHI [JP17H03809, JP19K06232]
- Innovative Area, Frontier Research on Chemical Communications [JP17H06406, JP19H04636, JP19K22266]
Paralytic shellfish toxins (PSTs) are the major neurotoxic contaminants of edible bivalves in Japan. Tetrodotoxin (TTX) was recently detected in bivalve shellfish around the world, drawing widespread attention. In Japan, high levels of TTX were reported in the digestive gland of the scallop, Patinopecten yessoensis, in 1993; however, no new data have emerged since then. In this study, we simultaneously analyzed PSTs and TTX in scallops cultured in a bay of east Japan using hydrophilic interaction chromatography (HILIC)-MS/MS. These scallops were temporally collected from April to December 2017. The highest concentration of PSTs (182 mu mol/kg, total congeners) in the hepatopancreas was detected in samples collected on May 23, lined to the cell density of the dinoflagellate, Alexandrium tamarense, in seawater around the scallops, whereas the highest concentration of TTX (421 nmol/kg) was detected in samples collected on August 22. Contrary to the previous report, temporal variation of the PSTs and TTX concentrations did not coincide. The highest concentration of TTX in the entire edible tissues was 7.3 mu g/kg (23 nmol/kg) in samples obtained on August 22, which was lower than the European Food Safety Authority (EFSA)-proposed threshold, 44 mu g TTX equivalents/kg shellfish meat. In addition, 12 beta-deoxygonyautoxin 3 was firstly identified in scallops.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据