期刊
LEUKEMIA & LYMPHOMA
卷 61, 期 2, 页码 437-444出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10428194.2019.1675875
关键词
SMYD2; expression; prognosis; acute lymphoblastic leukemia; pediatric
资金
- National Natural Science Foundation of China [81770202, 81470304]
- Zhejiang Science and Technology Department [2019C03032]
High expression of SET and MYND domain-containing protein 2(SMYD2) has been reported as a poor prognostic factor for various types of cancer. However, there are little published data about clinical significance of SMYD2 in children with ALL. We used real-time polymerase chain reaction (PCR) to detect SMYD2 expression in the bone marrow (BM) samples from 134 newly diagnosed children with ALL. Our data showed that children with ALL demonstrated significantly higher SMYD2 expression than control group (p?
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