相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Dysregulated expression of SKP2 and its role in hematological malignancies
Michal Kulinski et al.
LEUKEMIA & LYMPHOMA (2018)
HR+, HER2-Advanced Breast Cancer and CDK4/6 Inhibitors: Mode of Action, Clinical Activity, and Safety Profiles
Sarah L. Sammons et al.
CURRENT CANCER DRUG TARGETS (2017)
The combination of bortezomib with chemotherapy to treatrelapsed/refractory acute lymphoblastic leukaemia of childhood
Alice Bertaina et al.
BRITISH JOURNAL OF HAEMATOLOGY (2017)
The genetics and mechanisms of T cell acute lymphoblastic leukaemia
Laura Belver et al.
NATURE REVIEWS CANCER (2016)
Notch-Dependent Repression of miR-155 in the Bone Marrow Niche Regulates Hematopoiesis in an NF-κB-Dependent Manner
Lin Wang et al.
CELL STEM CELL (2014)
Therapeutic modulation of Notch signalling - are we there yet?
Emma R. Andersson et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers
Hongfang Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Developmental gene networks: a triathlon on the course to T cell identity
Mary A. Yui et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Divergent effects of supraphysiologic Notch signals on leukemia stem cells and hematopoietic stem cells
Mark Y. Chiang et al.
BLOOD (2013)
Pharmacological Inactivation of Skp2 SCF Ubiquitin Ligase Restricts Cancer Stem Cell Traits and Cancer Progression
Chia-Hsin Chan et al.
CELL (2013)
Relapsed childhood acute lymphoblastic leukaemia
Deepa Bhojwani et al.
LANCET ONCOLOGY (2013)
Therapeutic Targeting of the Cyclin D3:CDK4/6 Complex in T Cell Leukemia
Catherine M. Sawai et al.
CANCER CELL (2012)
The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis (vol 149, pg 1098, 2012)
Chia-Hsin Chan et al.
CELL (2012)
Specific Small Molecule Inhibitors of Skp2-Mediated p27 Degradation
Lily Wu et al.
CHEMISTRY & BIOLOGY (2012)
Intrathymic IL-7: The where, when, and why of IL-7 signaling during T cell development
Changwan Hong et al.
SEMINARS IN IMMUNOLOGY (2012)
The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs
Sonia Rodriguez et al.
BLOOD (2011)
Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies
Jon C. Aster et al.
JOURNAL OF PATHOLOGY (2011)
T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)
David I. Marks et al.
BLOOD (2009)
CSL-MAML-dependent Notch1 signaling controls T lineage-specific IL-7Rα gene expression in early human thymopoiesis and leukemia
Sara Gonzalez-Garcia et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease
Anupriya Agarwal et al.
BLOOD (2008)
Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer
Dan D. Hershko
CANCER (2008)
Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia
Mark Y. Chiang et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
The Immunological Genome Project: networks of gene expression in immune cells
Tracy S. P. Heng et al.
NATURE IMMUNOLOGY (2008)
Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP:: tipping the scales of cancer
David Frescas et al.
NATURE REVIEWS CANCER (2008)
Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines
Takeaki Dohda et al.
EXPERIMENTAL CELL RESEARCH (2007)
CD28 costimulation mediates transcription of SKP2 and CKS1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation
Leonard J. Appleman et al.
CELL CYCLE (2006)
Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1
Mark Y. Chiang et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
IL-7 promotes T cell proliferation through destabilization of p27Kip1
WQ Li et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27Kip1 degradation
LM Sarmento et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
IL-7-dependent human leukemia T-cell line as a valuable tool for drug discovery in T-ALL
JT Barata et al.
BLOOD (2004)
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
AP Weng et al.
SCIENCE (2004)
Degradation of p57Kip2 mediated by SCFSkp2 -: dependent ubiquitylation
T Kamura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
G Bornstein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Requirement for cyclin D3 in lymphocyte development and T cell leukemias
E Sicinska et al.
CANCER CELL (2003)
The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2
D Tedesco et al.
GENES & DEVELOPMENT (2002)
Notch signaling in hematopoiesis and early lymphocyte development
D Allman et al.
IMMUNOLOGICAL REVIEWS (2002)
Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27kip1
JT Barata et al.
BLOOD (2001)
Role of the F-box protein Skp2 in lymphomagenesis
E Latres et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Down-regulation of p27(Kip1) expression is required for development and function of T cells
T Tsukiyama et al.
JOURNAL OF IMMUNOLOGY (2001)
Cytokine-stimulated T lymphocyte proliferation is regulated by p27Kip11
SM Zhang et al.
JOURNAL OF IMMUNOLOGY (2000)
Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplication
K Nakayama et al.
EMBO JOURNAL (2000)