Magnetically induced Suzuki and Sonogashira reaction performed using recyclable, palladium-functionalized magnetite nanoparticles

A magnetically reusable, ligand-free palladium functionalized Fe3O4 catalyst system was successfully prepared. To overcome current problems such as the recyclability of the nanoparticle and the control and safety of the reaction, full advantage of the magnetite support was used. The palladium functionalized magnetite nanoparticle was removed by precipitation using a permanent magnet, while local heating, around the catalytic site, was induced using an external magnetic field. It was found that it was possible to perform the Suzuki reaction resulting in good to excellent conversions under air, with a magnetic field strength of 210 G and a frequency of 160 kHz. Despite the good results for the Suzuki reaction, it was not possible to perform the Sonogashira reaction magnetically due to an insufficient heat generation around the catalytic site. Further, the reusable catalyst system was recycled and reused for five times, resulting in a separable and straightforward catalyst system with the advantage of having full control of the reaction. (C) 2019 Elsevier B.V. All rights reserved.