期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 84, 期 23, 页码 15052-15062出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b01492
关键词
-
资金
- National Science Foundation (NSF) [1465003]
- National Institute of General Medical Sciences [U01GM120673]
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [1465003] Funding Source: National Science Foundation
A novel 8-O-picoloylated sialyl donor has been developed, and the performance of various picoloylated sialyl donors in glycosylations with primary glycosyl acceptors has been evaluated. 8-O-Picoloyl and 4,9-di-O-picoloyl sialyl donors produced moderate to excellent yields of disaccharides with complete alpha-stereoselectivities. Synergistic effects between picoloyl and the accompanying O-protecting groups (benzoyl vs acetyl) were evaluated, as well as the effects of triflic acid concentration on the 8-O-picoloyl donor. H-1 NMR analysis was also carried out to assess differences in the hydrogen-bonding
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据