Visible Light Photoredox-Catalyzed α-Alkylation of Cyclic Tertiary Arylamines

An efficient method was successfully developed to obtain cyclic beta-amino ketones via visible-light photoredox catalysis. With this catalytic system, vinyl azides and N-Ph pyrrolidines react to form cyclic beta-amino ketones by alpha-amino radical addition. This method provides a simple, mild, straightforward, and novel paradigm to prepare important beta-amino ketones.