期刊
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
卷 62, 期 2, 页码 145-148出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/JOM.0000000000001775
关键词
firefighters; inflammation; interleukin-6; natural disaster; stress
资金
- Deakin University
- Bushfire Cooperative Research Centre
Objectives: The purpose of this study was to determine the inflammatory response to a 12-hour wildfire suppression shift, in firefighters attending the Black Saturday natural disaster. Methods: Thirty-eight male volunteer firefighters provided venous blood samples before and after a 12-hour firefighting shift. Pre- to post-shift changes in pro-inflammatory (Interleukin [IL]-1 beta, IL-2, IL-6, IL-8, IL-12P70, granulocyte macrophage-colony stimulating factor [GM-CSF], tumor necrosis factor-alpha [TNF-alpha], interferongamma [IFN gamma]), and anti-inflammatory (IL-4, IL-5, IL-7, IL-10, IL-13) cytokines were measured with paired sample t tests, or Wilcoxon t tests for non-parametric data. Results: Interleukin (IL)-6 (P = 0 .003) and IL-8 (P = 0 .017) were significantly increased following 12-hours of wildfire suppression. There was also a significant decrease in IL-10 (P = 0 .021) . Conclusions: The observed acute inflammatory response may have resulted from multiple stressors including physical exertion, thermal strain, or smoke inhalation experienced during the shift, and may be a necessary response for the body to adapt to stressor exposure.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据