期刊
JOURNAL OF NUCLEAR MEDICINE
卷 61, 期 1, 页码 13-19出版社
SOC NUCLEAR MEDICINE INC
DOI: 10.2967/jnumed.119.228684
关键词
image-guided surgery; fluorescence imaging; nuclear medicine; bimodal tracers; multimodal
By contributing to noninvasive molecular imaging and radio-guided surgery, nuclear medicine has been instrumental in the realization of precision medicine. During the last decade, it has also become apparent that nuclear medicine (e.g., in the form of bimodal/hybrid tracers) can help to empower fluorescence-guided surgery. More specifically, when using hybrid tracers, lesions can be noninvasively identified and localized with a high sensitivity and precision (guided by the radioisotope) and ultimately resected under real-time optical guidance (fluorescent dye). This topical review discusses early clinical successes, preclinical directions, and key aspects that could have an impact on the future of this field.
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