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Virus-Host Coevolution with a Focus on Animal and Human DNA Viruses

期刊

JOURNAL OF MOLECULAR EVOLUTION
卷 88, 期 1, 页码 41-56

出版社

SPRINGER
DOI: 10.1007/s00239-019-09913-4

关键词

Virus; Coevolution; Antiviral defence; Endogenous viral elements

资金

  1. MTA Centre for Agricultural Research (MTA ATK)
  2. OMA Foundation [101ou6]
  3. National Research, Development and Innovation Office [K127916, NN128309]
  4. Hungarian Academy of Sciences

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Viruses have been infecting their host cells since the dawn of life, and this extremely long-term coevolution gave rise to some surprising consequences for the entire tree of life. It is hypothesised that viruses might have contributed to the formation of the first cellular life form, or that even the eukaryotic cell nucleus originates from an infection by a coated virus. The continuous struggle between viruses and their hosts to maintain at least a constant fitness level led to the development of an unceasing arms race, where weapons are often shuttled between the participants. In this literature review we try to give a short insight into some general consequences or traits of virus-host coevolution, and after this we zoom in to the viral clades of adenoviruses, herpesviruses, nucleo-cytoplasmic large DNA viruses, polyomaviruses and, finally, circoviruses.

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