期刊
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
卷 34, 期 19, 页码 3259-3268出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14767058.2019.1678142
关键词
Perinatal outcomes; periodontal treatment; pregnancy; randomized controlled trials
Periodontal treatment during pregnancy significantly reduces the risks of perinatal mortality and preterm birth, while also increasing birth weight.
Objective: To assess the effect of periodontal treatment during pregnancy on maternal, fetal and neonatal outcomes. Methods: This is a systematic review and meta-analysis of randomized controlled trials that evaluated the effect of treatment of periodontal diseases on pregnancy outcomes. Primary outcome was perinatal mortality. Secondary outcomes were maternal and neonatal morbidity. Outcomes were pooled using fix-effect or random effects models and presented as risk ratio (RR), or mean difference (MD), and 95% confidence interval (CI). Results: Twenty randomized controlled trials involving 8171 participants were included in this study. Periodontal treatment during pregnancy was associated with significantly decreased risk of perinatal mortality [N?=?5942; RR?=?0.53 (0.30?0.93); p?=?.03; heterogeneity (I-2) = 0%, Number needed to treat (NNT): 162]. Periodontal treatment during pregnancy reduced risks of preterm birth [N?=?7335; RR?=?0.78 (0.62?0.98); p?=?.03; I-2 = 72%, NNT?=?37]. Periodontal treatment during pregnancy significantly increased birthweight (gram) [N?=?4708; MD?=?200.79 (63.34?337.24); p?=?.004; I-2 = 93%]. Periodontal treatment during pregnancy was not associated with preeclampsia, gestational diabetes, cesarean section, small for gestational age, or congenital malformations. Conclusion: Periodontal treatment during pregnancy reduces the risks of perinatal mortality and preterm birth, and improves birth weight.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据