Noncovalent force spectroscopy using wide-field optical and diamond-based magnetic imaging

A realization of the force-induced remnant magnetization spectroscopy technique of specific biomolecular binding is presented, where detection is accomplished with wide-field optical and diamond-based magnetometry using an ensemble of nitrogen-vacancy color centers. This diamond-based technique that has both optical and magnetic detection modalities may be adapted for massively parallel screening of arrays of nanoscale samples. Published under license by AIP Publishing.