期刊
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 67, 期 43, 页码 11825-11838出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.jafc.9b03566
关键词
bioactive peptides; microalgae peptides; peptidomics; mass spectrometry; cardiovascular disease; microalgae; LC-MS; cardiovascular prevention; peptide quantification
资金
- China Scholarship Council
- Cariplo Foundation project SUPER-HEMP: Sustainable Process for Enhanced Recovery of Hempseed Oil [2017-1005]
- project COMPETiTiVE: Claims of Olive oil to iMProvE The market ValuE of the product - AGER
There is now great interest in food protein hydrolysates and food-derived peptides, because they may provide numerous health benefits. Among other foodstuffs, microalgae appear to be sustainable sources of proteins and bioactive peptides that can be exploited in foods and functional formulations. This review considers protein hydrolysates and individual peptides that may be relevant in cardiovascular disease prevention because they mimic the functions of mediators involved in pathologic processes that represent relevant risk factors for cardiovascular disease development, such as hypercholesterolemia, hypertension, diabetes, inflammation, and oxidative status. Some of these peptides are also multifunctional (i.e., they offer more than one benefit). Moreover, the most efficient techniques for protein extraction and hydrolyzation are commented on, as well as the best methodologies for high-throughput detection and quantification. Finally, current challenges and critical issues are discussed.
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