期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 20, 期 21, 页码 -出版社
MDPI
DOI: 10.3390/ijms20215376
关键词
sepsis; pathogenesis; biomarkers; therapeutic drugs
资金
- National Natural Science Foundation of China [81803547]
- Natural Science Foundation of Fujian Province, China [2018J01720, 2017J01621]
- Innovative Research Teams Program II of Fujian Normal University in China [IRTL1703, FZSKG2018013]
- Public Service Platform for Industrialization Development Technology of Marine Biological Medicine and Product of State Oceanic Administration
Sepsis is defined as a life-threatening organ dysfunction caused by a host's dysfunctional response to infection. Although the treatment of sepsis has developed rapidly in the past few years, sepsis incidence and mortality in clinical treatment is still climbing. Moreover, because of the diverse manifestations of sepsis, clinicians continue to face severe challenges in the diagnosis, treatment, and management of patients with sepsis. Here, we review the recent development in our understanding regarding the cellular pathogenesis and the target of clinical diagnosis of sepsis, with the goal of enhancing the current understanding of sepsis. The present state of research on targeted therapeutic drugs is also elaborated upon to provide information for the treatment of sepsis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据