相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Liquid chromatography coupled to mass spectrometry for metabolite profiling in the field of drug discovery
Javier Saurina et al.
EXPERT OPINION ON DRUG DISCOVERY (2019)
FGF21 as Modulator of Metabolism in Health and Disease
Caterina Tezze et al.
FRONTIERS IN PHYSIOLOGY (2019)
HCF-1 Regulates De Novo Lipogenesis through a Nutrient-Sensitive Complex with ChREBP
Elizabeth A. Lane et al.
MOLECULAR CELL (2019)
Carbohydrate Sensing Through the Transcription Factor ChREBP
Paula Ortega-Prieto et al.
FRONTIERS IN GENETICS (2019)
Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes
A. Kaisanlahti et al.
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2019)
MondoA drives muscle lipid accumulation and insulin resistance
Byungyong Ahn et al.
JCI INSIGHT (2019)
Interaction between hormone-sensitive lipase and ChREBP in fat cells controls insulin sensitivity
Pauline Morigny et al.
NATURE METABOLISM (2019)
Global aetiology and epidemiology of type 2 diabetes mellitus and its complications
Yan Zheng et al.
NATURE REVIEWS ENDOCRINOLOGY (2018)
Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis
Joan Sanchez-Gurmaches et al.
CELL METABOLISM (2018)
Sugar sensing by ChREBP/Mondo-Mlx - new insight into downstream regulatory networks and integration of nutrient-derived signals
Essi Havula et al.
CURRENT OPINION IN CELL BIOLOGY (2018)
Activation of Nrf2 Is Required for Normal and ChREBP alpha-Augmented Glucose-Stimulated beta-Cell Proliferation
Anil Kumar et al.
DIABETES (2018)
Current anti-diabetic agents and their molecular targets: A review
Nagaraju Kerru et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity
Julien Bricambert et al.
NATURE COMMUNICATIONS (2018)
Regulation and Metabolic Significance of De Novo Lipogenesis in Adipose Tissues
Ziyi Song et al.
NUTRIENTS (2018)
T3 and Glucose Coordinately Stimulate ChREBP-Mediated Ucp1 Expression in Brown Adipocytes From Male Mice
Liora S. Katz et al.
ENDOCRINOLOGY (2018)
mTOR controls ChREBP transcriptional activity and pancreatic β cell survival under diabetic stress
Gia Cac Chau et al.
JOURNAL OF CELL BIOLOGY (2017)
MondoA/ChREBP: The usual suspects of transcriptional glucose sensing; Implication in pathophysiology
Paul Richards et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2017)
Retinol saturase coordinates liver metabolism by regulating ChREBP activity
Steffi Heidenreich et al.
NATURE COMMUNICATIONS (2017)
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20
Gan Liu et al.
NATURE COMMUNICATIONS (2017)
Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport
Archana Vijayakumar et al.
CELL REPORTS (2017)
A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response
Alison Iroz et al.
CELL REPORTS (2017)
Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in mice
Bo Xia et al.
PLOS GENETICS (2017)
Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice
Tara Jois et al.
MOLECULAR METABOLISM (2017)
A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism
Ffolliott M. Fisher et al.
MOLECULAR METABOLISM (2017)
Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming
Adilson Guilherme et al.
MOLECULAR METABOLISM (2017)
Sweet Sixteenth for ChREBP: Established Roles and Future Goals
Aya Abdul-Wahed et al.
CELL METABOLISM (2017)
Tissue Specific Effects of Dietary Carbohydrates and Obesity on ChREBP alpha and ChREBP beta Expression
Alexis D. Stamatikos et al.
LIPIDS (2016)
Understanding the Physiology of FGF21
Ffolliott Martin Fisher et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 78 (2016)
A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism
Leonela Amoasii et al.
GENES & DEVELOPMENT (2016)
Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP) ROLE OF AMP AS AN ALLOSTERIC INHIBITOR
Shogo Sato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling
Byungyong Ahn et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux
Varman T. Samuel et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Adipose tissue regulates insulin sensitivity: role of adipogenesis, de novo lipogenesis and novel lipids
U. Smith et al.
JOURNAL OF INTERNAL MEDICINE (2016)
Identification of HNF-4α as a key transcription factor to promote ChREBP expression in response to glucose
Jian Meng et al.
SCIENTIFIC REPORTS (2016)
Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β Cells
Soren Fisker Schmidt et al.
CELL REPORTS (2016)
Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop
Gu Jing et al.
MOLECULAR METABOLISM (2016)
Adipose Tissue Remodeling: its Role in energy Metabolism and Metabolic Disorders
Sung Sik Choe et al.
FRONTIERS IN ENDOCRINOLOGY (2016)
Adipose tissue: an endocrine organ playing a role in metabolic regulation
Andrea Booth et al.
HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION (2016)
Pancreatic regulation of glucose homeostasis
Pia V. Roeder et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2016)
C771G (His241Gln) Polymorphism of MLXIPL Gene, TG levels and coronary artery disease: A case control study
Asghar Ghasemi et al.
ANATOLIAN JOURNAL OF CARDIOLOGY (2015)
Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell Proliferation
Pili Zhang et al.
DIABETES (2015)
FABP4-Cre Mediated Expression of Constitutively Active ChREBP Protects Against Obesity, Fatty Liver, and Insulin Resistance
Alli M. Nuotio-Antar et al.
ENDOCRINOLOGY (2015)
The Glucose Sensor ChREBP Links De Novo Lipogenesis to PPARγ Activity and Adipocyte Differentiation
Nicole Witte et al.
ENDOCRINOLOGY (2015)
Physical activity and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis
Dagfinn Aune et al.
EUROPEAN JOURNAL OF EPIDEMIOLOGY (2015)
The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling
Liam C. Hunt et al.
GENES & DEVELOPMENT (2015)
Excess Mortality among Persons with Type 2 Diabetes
Mauro Tancredi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
The Economic Costs of Type 2 Diabetes: A Global Systematic Review
Till Seuring et al.
PHARMACOECONOMICS (2015)
Insulin resistance and impaired adipogenesis
Birgit Gustafson et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2015)
The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis
Chiara Saponaro et al.
NUTRIENTS (2015)
MondoA deficiency enhances sprint performance in mice
Minako Imamura et al.
BIOCHEMICAL JOURNAL (2014)
Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects
Mark M. Yore et al.
CELL (2014)
Nonalcoholic Fatty Liver Disease, Hepatic Insulin Resistance, and Type 2 Diabetes
Andreas L. Birkenfeld et al.
HEPATOLOGY (2014)
Williams-Beuren Syndrome Is a Genetic Disorder Associated with Impaired Glucose Tolerance and Diabetes in Childhood and Adolescence: New Insights from a Longitudinal Study
Stefano Stagi et al.
HORMONE RESEARCH IN PAEDIATRICS (2014)
Risk Factors Contributing to Type 2 Diabetes and Recent Advances in the Treatment and Prevention
Yanling Wu et al.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2014)
Pancreatic Metabolism, Blood Flow, and β-Cell Function in Obese Humans
Henri Honka et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)
Prevention and management of type 2 diabetes: dietary components and nutritional strategies
Sylvia H. Ley et al.
LANCET (2014)
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
Rachel J. Perry et al.
NATURE (2014)
De nova lipogenesis in health and disease
Fatima Ameer et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2014)
Brown fat fuel utilization and thermogenesis
Kristy L. Townsend et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)
Mechanism linking diabetes mellitus and obesity
Abdullah S. Al-Goblan et al.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY (2014)
Association between CETP, MLXIPL, and TOMM40 polymorphisms and serum lipid levels in a Latvian population
I. Radovica et al.
META GENE (2014)
Decreased Transcription of ChREBP-α/β Isoforms in Abdominal Subcutaneous Adipose Tissue of Obese Adolescents With Prediabetes or Early Type 2 Diabetes Associations With Insulin Resistance and Hyperglycemia
Romy Kursawe et al.
DIABETES (2013)
The use of technology to promote physical activity in Type 2 diabetes management: a systematic review
J. Connelly et al.
DIABETIC MEDICINE (2013)
Glucose Induces Protein Targeting to Glycogen in Hepatocytes by Fructose 2,6-Bisphosphate-Mediated Recruitment of MondoA to the Promoter
John L. Petrie et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Farnesoid X Receptor Inhibits the Transcriptional Activity of Carbohydrate Response Element Binding Protein in Human Hepatocytes
Sandrine Caron et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health
Leah Eissing et al.
NATURE COMMUNICATIONS (2013)
Mondo/ChREBP-Mlx-Regulated Transcriptional Network Is Essential for Dietary Sugar Tolerance in Drosophila
Essi Havula et al.
PLOS GENETICS (2013)
PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner
Kari T. Chambers et al.
MOLECULAR METABOLISM (2013)
Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes
Catherine Arden et al.
BIOCHEMICAL JOURNAL (2012)
Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α
Eric A. Hanse et al.
CELL CYCLE (2012)
ChREBP Mediates Glucose-Stimulated Pancreatic β-Cell Proliferation
Mallikarjuna R. Metukuri et al.
DIABETES (2012)
Carbohydrate response element-binding protein (ChREBP) plays a pivotal role in beta cell glucotoxicity
N. Poungvarin et al.
DIABETOLOGIA (2012)
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
Fadila Benhamed et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver
Renaud Dentin et al.
JOURNAL OF HEPATOLOGY (2012)
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism
Mark A. Herman et al.
NATURE (2012)
Glucose sensing by ChREBP/MondoA-Mlx transcription factors
Essi Havula et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2012)
ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity
Carmen Hurtado del Pozo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2011)
O-G1cNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver
Celine Guinez et al.
DIABETES (2011)
ChREBP Mediates Glucose Repression of Peroxisome Proliferator-activated Receptor α Expression in Pancreatic β-Cells
Michael Boergesen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Importin-α Protein Binding to a Nuclear Localization Signal of Carbohydrate Response Element-Binding Protein (ChREBP)
Qiang Ge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP)
Ming V. Li et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice
Julien Bricambert et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
Rongbin Zhou et al.
NATURE IMMUNOLOGY (2010)
Hepatic overexpression of dominant negative Mlx improves metabolic profile in diabetes-prone C57BL/6J mice
Katsumi Iizuka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
cAMP opposes the glucose-mediated induction of the L-PK gene by preventing the recruitment of a complex containing ChREBP, HNF4α, and CBP
Susan J. Burke et al.
FASEB JOURNAL (2009)
Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes
Katsumi Iizuka et al.
FEBS LETTERS (2009)
Glucose-stimulated Expression of Txnip Is Mediated by Carbohydrate Response Element-binding Protein, p300, and Histone H4 Acetylation in Pancreatic Beta Cells
Hyunjoo Cha-Molstad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Identification and function of phosphorylation in the glucose-regulated transcription factor ChREBP
Nikolas G. Tsatsos et al.
BIOCHEMICAL JOURNAL (2008)
Thioredoxin-interacting protein -: A critical link between glucose toxicity and β-cell apoptosis
Junqin Chen et al.
DIABETES (2008)
Regulation of Nuclear Import/Export of Carbohydrate Response Element-binding Protein (ChREBP) INTERACTION OF AN α-HELIX OF ChREBP WITH THE 14-3-3 PROTEINS AND REGULATION BY PHOSPHORYLATION
Haruhiko Sakiyama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Glucose sensing by MondoA:Mlx complexes:: A role for hexokinases and direct regulation of thioredoxin-interacting protein expression
Carrie A. Stoltzman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
ChREBP•Mlx is the principal mediator of glucose-induced gene expression in the liver
Lin Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis
Kosaku Uyeda et al.
CELL METABOLISM (2006)
Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice
Katsumi Iizuka et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)
Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice
Renaud Dentin et al.
DIABETES (2006)
MondoA-Mlx heterodimers are candidate sensors of cellular energy status: Mitochondrial localization and direct regulation of glycolysis
Christopher L. Sans et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Glucose as a regulator of eukaryotic gene transcription
HC Towle
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2005)
Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces β-cell apoptosis
AH Minn et al.
ENDOCRINOLOGY (2005)
Direct role of ChREBP•Mlx in regulating hepatic glucose-responsive genes
L Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes
AK Stoeckman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3
G Merla et al.
HUMAN MOLECULAR GENETICS (2004)
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis
K Iizuka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
A novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex
AL Eilers et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Mechanism for fatty acid sparing effect on glucose-induced transcription - Regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase
T Kawaguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein
T Kawaguchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
H Yamashita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a Max-like network
AN Billin et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Mlx, a new Max-Like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?
G Meroni et al.
ONCOGENE (2000)
分享论文
