4.5 Article

Mechanical response of cardiovascular stents under vascular dynamic bending

期刊

BIOMEDICAL ENGINEERING ONLINE
卷 15, 期 -, 页码 -

出版社

BMC
DOI: 10.1186/s12938-016-0135-8

关键词

Cardiovascular stent; Vascular dynamic bending (VDB); Vascular pulsation (VP); Stent fatigue; Explicit-implicit coupling simulation method

资金

  1. National High-Tech Program of China [2006AA02A139]
  2. NSFC [11372257, 1330031]
  3. National Science Foundation [CBET-1113040]
  4. National Institute of Health [EB015105]
  5. doctorial innovation fund of SWJTU

向作者/读者索取更多资源

Backround: Currently, the effect of vascular dynamic bending (VDB) has not been fully considered when studying cardiovascular stents' long-term mechanical properties, as the previous studies about stent's mechanical properties mostly focus on the effect of vascular pulsation (VP). More and more clinical reports suggested that the effect of VDB have a significant impact on stent. Methods: In this paper, an explicit-implicit coupling simulation method was applied to analyze the mechanical responses of cardiovascular stents considering the effect of VDB. The effect of VP on stent mechanical properties was also studied and compared to the effect of VDB. Results: The results showed that the dynamic bending deformation occurred in stents due to the effect of VDB. The effects of VDB and VP resulted in alternating stress states of the stent, while the VDB alternate stresses effective on the stent were almost three times larger than that of the VP. The stress concentration under VDB mainly occurred in bridge struts and the maximal stress was located in the middle loops of the stent. However, the stress distributed uniformly in the stents under the effect of VP. Stent fracture occurred more frequently as a result of VDB with the predicted fracture position located in the bridging struts of the stent. These results are consistent with the reported data in clinical literatures. The stress of the vessel under VDB was higher, than that caused by VP. Conclusions: The results showed that the effect of VDB has a significant impact on the stent's stress distribution, fatigue performance and overall stress on the vessel, thus it is necessary to be considered when analyzing stent's long-term mechanical properties. Meanwhile, the results showed that the explicit-implicit coupling simulation can be applied to analyze stent mechanical properties.

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