4.7 Article

A Novel Weakly Supervised Multitask Architecture for Retinal Lesions Segmentation on Fundus Images

期刊

IEEE TRANSACTIONS ON MEDICAL IMAGING
卷 38, 期 10, 页码 2434-2444

出版社

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMI.2019.2906319

关键词

Lesions; Retina; Image segmentation; Diseases; Training; Task analysis; Feature extraction; Computer-aided diagnostic; fundus imaging; lesions segmentations; retina; screening

资金

  1. Natural Sciences and Engineering Reseach Council of Canada (NSERC)

向作者/读者索取更多资源

Obtaining the complete segmentation map of retinal lesions is the first step toward an automated diagnosis tool for retinopathy that is interpretable in its decision-making. However, the limited availability of ground truth lesion detection maps at a pixel level restricts the ability of deep segmentation neural networks to generalize over large databases. In this paper, we propose a novel approach for training a convolutional multi-task architecture with supervised learning and reinforcing it with weakly supervised learning. The architecture is simultaneously trained for three tasks: segmentation of red lesions and of bright lesions, those two tasks done concurrently with lesion detection. In addition, we propose and discuss the advantages of a new preprocessing method that guarantees the color consistency between the raw image and its enhanced version. Our complete system produces segmentations of both red and bright lesions. The method is validated at the pixel level and per-image using four databases and a cross-validation strategy. When evaluated on the task of screening for the presence or absence of lesions on the Messidor image set, the proposed method achieves an area under the ROC curve of 0.839, comparable with the state-of-the-art.

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