4.7 Review

Metabolic dependencies and vulnerabilities in leukemia

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Letter Hematology

Identification of sphingosine kinase 1 as a therapeutic target in B-lineage acute lymphoblastic leukaemia

Craig T. Wallington-Beddoe et al.

BRITISH JOURNAL OF HAEMATOLOGY (2019)

Article Hematology

Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia

Mark A. Gregory et al.

EXPERIMENTAL HEMATOLOGY (2018)

Article Multidisciplinary Sciences

Clonal evolution mechanisms in NT5C2 mutant/relapsed acute lymphoblastic leukaemia

Gannie Tzoneva et al.

NATURE (2018)

Article Medicine, General & Internal

Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML

C. D. DiNardo et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Cell Biology

Statins enhance efficacy of venetoclax in blood cancers

J. Scott Lee et al.

SCIENCE TRANSLATIONAL MEDICINE (2018)

Review Biotechnology & Applied Microbiology

Forodesine in the treatment of relapsed/refractory peripheral T-cell lymphoma: an evidence-based review

Shinichi Makita et al.

ONCOTARGETS AND THERAPY (2018)

Article Multidisciplinary Sciences

Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia

Jacqueline Lehmann-Che et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

Benjamin D. Hopkins et al.

NATURE (2018)

Article Oncology

The Association of Dyslipidemia With Chronic Lymphocytic Leukemia: A Population-Based Study

Lee Mozessohn et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2017)

Article Oncology

The Association of Dyslipidemia With Chronic Lymphocytic Leukemia: A Population-Based Study

Lee Mozessohn et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2017)

Review Oncology

Genomics of Acute Myeloid Leukemia Diagnosis and Pathways

Lars Bullinger et al.

JOURNAL OF CLINICAL ONCOLOGY (2017)

Article Multidisciplinary Sciences

Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia

Ayuna Hattori et al.

NATURE (2017)

Article Biochemistry & Molecular Biology

The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia

Nina Fenouille et al.

NATURE MEDICINE (2017)

Article Biochemistry & Molecular Biology

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

Luisa Cimmino et al.

Article Oncology

A link between hypercholesterolemia and chronic lymphocytic leukemia

Signy Chow et al.

LEUKEMIA & LYMPHOMA (2016)

Review Hematology

Review: Aberrant EVI1 expression in acute myeloid leukaemia

Adil A. Hinai et al.

BRITISH JOURNAL OF HAEMATOLOGY (2016)

Article Biochemistry & Molecular Biology

Metabolic Heterogeneity in Human Lung Tumors

Christopher T. Hensley et al.

Article Biochemistry & Molecular Biology

PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2

Natalie J. German et al.

MOLECULAR CELL (2016)

Article Multidisciplinary Sciences

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

Koichi Oshima et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

SIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation

Shuang-Nian Xu et al.

SCIENTIFIC REPORTS (2016)

Review Oncology

The genetics and mechanisms of T cell acute lymphoblastic leukaemia

Laura Belver et al.

NATURE REVIEWS CANCER (2016)

Review Cell Biology

Metabolic pathways promoting cancer cell survival and growth

Lindsey K. Boroughs et al.

NATURE CELL BIOLOGY (2015)

Article Genetics & Heredity

The genomic landscape of juvenile myelomonocytic leukemia

Elliot Stieglitz et al.

NATURE GENETICS (2015)

Article Biochemistry & Molecular Biology

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

Daniel Herranz et al.

NATURE MEDICINE (2015)

Review Oncology

Genomics in acute lymphoblastic leukaemia: insights and treatment implications

Kathryn G. Roberts et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2015)

Article Biochemistry & Molecular Biology

Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis

Ying-Hua Wang et al.

Article Oncology

Intravenous Vitamin C and Cancer: A Systematic Review

Heidi Fritz et al.

INTEGRATIVE CANCER THERAPIES (2014)

Article Biochemistry & Molecular Biology

A NOTCH 1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia

Daniel Herranz et al.

NATURE MEDICINE (2014)

Article Multidisciplinary Sciences

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

Cosimo Commisso et al.

NATURE (2013)

Article Multidisciplinary Sciences

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

Jaekyoung Son et al.

NATURE (2013)

Article Genetics & Heredity

Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia

Julia A. Meyer et al.

NATURE GENETICS (2013)

Article Biochemistry & Molecular Biology

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL

Gannie Tzoneva et al.

NATURE MEDICINE (2013)

Article Multidisciplinary Sciences

Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers

Michael Pourdehnada et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

Haoqiang Ying et al.

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Article Cell Biology

Pancreatic cancers require autophagy for tumor growth

Shenghong Yang et al.

GENES & DEVELOPMENT (2011)

Article Cell Biology

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

Jessie Yanxiang Guo et al.

GENES & DEVELOPMENT (2011)

Article Cell Biology

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

Rebecca Lock et al.

MOLECULAR BIOLOGY OF THE CELL (2011)

Article Multidisciplinary Sciences

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

Johannes Zuber et al.

NATURE (2011)

Article Hematology

Pegylated arginase I: a potential therapeutic approach in T-ALL

Claudia P. Hernandez et al.

Article Biochemistry & Molecular Biology

Myc-dependent Mitochondrial Generation of Acetyl-CoA Contributes to Fatty Acid Biosynthesis and Histone Acetylation during Cell Cycle Entry

Fionnuala Morrish et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Medicine, Research & Experimental

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

Ismael Samudio et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Multidisciplinary Sciences

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

Frank Weinberg et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

IDH2 Mutations in Patients with D-2-Hydroxyglutaric Aciduria

Martijn Kranendijk et al.

SCIENCE (2010)

Article Multidisciplinary Sciences

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Lenny Dang et al.

NATURE (2009)

Article Medicine, General & Internal

Mutation in TET2 in Myeloid Cancers

Francois Delhommeau et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Medicine, General & Internal

Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome

Elaine R. Mardis et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Medicine, General & Internal

IDH1 and IDH2 Mutations in Gliomas

Hai Yan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Multidisciplinary Sciences

Global Regulation of Nucleotide Biosynthetic Genes by c-Myc

Yen-Chun Liu et al.

PLOS ONE (2008)

Article Multidisciplinary Sciences

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

David R. Wise et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

The crystal structure of a mammalian fatty acid synthase

Timm Maier et al.

SCIENCE (2008)

Article Multidisciplinary Sciences

Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

Ralph J. DeBerardinis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

Teresa Palomero et al.

NATURE MEDICINE (2007)

Article Multidisciplinary Sciences

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

Teresa Palomero et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

Histone demethylation by a family of JmjC domain-containing proteins

Y Tsukada et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis

F Li et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Article Nutrition & Dietetics

Glutathione metabolism and its implications for health

GY Wu et al.

JOURNAL OF NUTRITION (2004)

Article Multidisciplinary Sciences

Live-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity

B Stiles et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Medicine, General & Internal

Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment

A Holleman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

Article Biochemistry & Molecular Biology

Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents

VL Schramm

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2002)

Article Biochemistry & Molecular Biology

Accelerated publication -: Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc

RC Osthus et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)